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… know through professional circles in some way or another. But today, we have someone who, weirdly, I haven’t, I think, … heard of anthropology. This is– I grew up in a very rural, small town. We didn’t have AP or IB courses or any of these … bugs out of that or whatever. And so I was intrigued by the small section in the book about the conflicts between ideas …

… which is a liver toxin when humans accidentally eat it, but it has a really fun and interesting biosynthetic … chains of amino acids. “Peptide” is just another word for a small protein. And it turns out that a lot of natural … that grab amino acids and stick them together to make small peptides. Those are fun, because the host organism can …

… and, so, I don’t really have any trouble understanding him, but I know from the download stats that we actually have a … toxic molecules, and that human beings know, today, for small molecules. So they’re in the picomolar range. ALISON: … it’s really remarkable in terms of a novel mechanism, how a small molecule can kill. So that immediately inspired people …

… trying really hard just for you. And the JGI Comms team. But mostly you. Anyway…I’m really happy today to be handing … quite as true as we once thought it was. DAN: So it's very empirical then how you tackle this. BETSY PARKINSON: Yeah. … So cis versus trans in order to cyclize at that small of a ring, which is highly unfavorable. DAN: Oh, I did …

… isn’t as good as what you’ll hear in other episodes, but it’s not terrible. I was able to clean it up quite a … cases. MARC: Yeah, and in some cases of really extremely small genomes, like symbionts that can’t live without their … For those that aren’t familiar with Jo, she’s really a champion of many different things in microbiology and biology …

I’m really looking forward to getting them out to you all. But for now, here is episode 10 of Natural Prodcast, the … any water that washed down off the hills might carry small pieces of gold along with them and end up in the beds … then I would take a couple of the domains, which are small pieces of the sequence of a polyketide synthase. Each …

… we can identify most secondary metabolism pathways now, but there’s still almost certainly unusual things that we … yeah, so these guys, it turns out, produce lots of really small molecules that they use to communicate – lots of … spots around that?  ALISON: Oh, they’re so much smaller. Streptococcus is losing! DAN: Yeah, so that’s …

… papers. Applicants may submit up to two proposals per year (but may be listed as co-PI on an unlimited number of …