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… and, so, I don’t really have any trouble understanding him, but I know from the download stats that we actually have a … toxic molecules, and that human beings know, today, for small molecules. So they’re in the picomolar range. ALISON: … it’s really remarkable in terms of a novel mechanism, how a small molecule can kill. So that immediately inspired people …

… that would be Katherine. Dan Udwary: Right. Kate Duncan: But most people that know me call me Kate. Dan Udwary: … around countries. And I was actually in Croatia on a small island off the coast in the Adriatic Sea, and I … And you kind of build your knowledge from the things, the small pieces that you know, to expand that out. And then you …

I’m really looking forward to getting them out to you all. But for now, here is episode 10 of Natural Prodcast, the … any water that washed down off the hills might carry small pieces of gold along with them and end up in the beds … then I would take a couple of the domains, which are small pieces of the sequence of a polyketide synthase. Each …

… isn’t as good as what you’ll hear in other episodes, but it’s not terrible. I was able to clean it up quite a … cases. MARC: Yeah, and in some cases of really extremely small genomes, like symbionts that can’t live without their … so we were at Warp Drive Bio. This was in Cambridge, Mass. Small… I guess we’d call it a small startup – while we were …

… we can identify most secondary metabolism pathways now, but there’s still almost certainly unusual things that we … yeah, so these guys, it turns out, produce lots of really small molecules that they use to communicate – lots of … spots around that?  ALISON: Oh, they’re so much smaller. Streptococcus is losing! DAN: Yeah, so that’s …

… trying really hard just for you. And the JGI Comms team. But mostly you. Anyway…I’m really happy today to be handing … So cis versus trans in order to cyclize at that small of a ring, which is highly unfavorable. DAN: Oh, I did … asking, could we try and do this with something that's smaller than the enzyme - some bio-organic type catalyst? …

… are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think you’ll … hard to make a full story out of that yet. So we have some small, little stories, all the time. We have compared three … want to make a full story. And so far, I have a lot of smaller stories that I still have to wrap up into one big …

A little bit of a bonus episode, since I’m off schedule, but this is an important one that wanted to get out there as … the normal amount that we get, which is already a fairly small number. We’re a very niche podcast. And so maybe if we … what? There must be a lot of competition as the lake gets smaller. These organisms that live in the water column are …

… tedious technical problems with editing the recording. But I recently changed the audio editing suite I use which … FRANCISCO BARONA-GOMEZ: Exactly. And I have just written a small piece where we discuss the future of merging … It’s hard to– most people will not go and purify the small peak on a HPLC, because that’s a hard one. They will …