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… al. (2021) CheckV assesses the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . … Science  356: 82-85 Ovchinnikov S. et al. (2017) Protein structure determination using metagenome sequence data. … al. (2015) Microbial species delineation using whole genome sequences. Nucleic Acids Res. 43(14):6761-71 Kyrpides NC et …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, … and single cells. This effort uncovers novel genes, protein families, and pathways, enhancing our understanding … capability of microbial communities based on their metagenome sequence, in the context of reference isolate …

… attraction to natural products was dual, the beauty of the structures and also the challenge and thinking about making … do engineering to improve the physical properties of a protein and make it easier to work with. But sometimes, what … And so there are different ways that we decided which sequences made it onto that list. So the majority of them …

Yeah. DAN: Yeah. So that involves figuring out the structure of that pure molecule. And that can that can take … DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary metabolites. Do you …

The Sequencing Technologies Group applies cutting edge molecular capabilities and state-of-the-art next-generation …

… families known up until now, and identified many novel structure predictions,” said lead author on the paper … (IMG/M) database, they successfully crafted the Novel Metagenome Protein Families (NMPF) Catalog.  “We can now … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists …

The Facilities Integrating Collaborations for User Science (FICUS) call represents a unique … technologies available at JGI and EMSL such as DNA-SIP, Protein SIP, Flux Balance analysis with metabolites, Isotope …

The IMG group owns and maintains integral components of JGI’s … specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within … resource for analysis and annotation of genome and metagenome datasets in a comprehensive comparative context. …

The Micro-Scale Applications group explores the genetic makeup of natural microbial communities …

… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of … datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes (MAGs), and 40,000+ metagenomes … so no programming knowledge and no dedicated compute infrastructure is required to perform computational analysis. …

Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards … Scientist Program is for faculty-level scientists who are seeking to build upon their line of scientific inquiry by …