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… projects of relevance to Department of Energy (DOE)  Mission Areas . Through this program, the DOE aims to advance … is for PIs who have never led a JGI project, and the Functional Genomics call is for projects that translate genomic information into biological function. The  New Investigator and …

… QUAVE: So the other thing that we do on the ground with the communities themselves is really think about what are their … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … like. And so we take genes that we think are going to be similar, and we do a homology search. We compare those … of the IMG data portal , which is a larger portal for microbial genomics. IMG stands for Integrated Microbial …

… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hello, and welcome back for Episode … genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural … opens up new doors. Yeah. Yeah, your origin sounds somewhat similar to mine. I was talking to an organic chemistry …

… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so … parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … our understanding of the impacts of these viruses on microbiome processes is still limited. One key challenge …

… the user programs at the JGI, and I’m also the head of the microbial genome program. And I’m a scientist here. And have … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we … DOE Auspice Statement in any publications. And that can be found on our website as well. It’s also included in the …

… like, yeah, there’s some part to the molecule that are similar, and there’s some bits that are different. And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… are, even if primary metabolism seems to be very similar. But how fast they switch, and then you see really– … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … what I always expected. Because we know from soil that communities change very much, that whenever it rains, then …

… the National Institutes of Health and the National Science Foundation to create international partnerships in … to try and create an open source database of all known microbial natural products. So if you think about natural … whether or not gene clusters which don’t look that similar actually produce similar products. So I think we …

… Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent … The research efforts of the group have concentrated in demonstrating the power of data science in …

… outreach program to get kids interested in microbiology and microbial chemistry. All good stuff, and I hope you enjoy … analysis where we look for other receptors with sequence similarity to some of these known ones. What's really … as what we initiated our search around. And so we found examples of those, and then looked for NRPSs nearby, …

… The Facilities Integrating Collaborations for User Science (FICUS) call represents a unique … utilize a broad range of the capabilities across at least two of the facilities, and generate datasets beyond what … provides customized analysis, the JGI also participates in publication of results. …