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The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and micro-eukaryoes, along with their … and viral activity, transcription regulation, and noncoding RNAs in microbiomes. The insights from this work have the …

… is alive and well and doing very well. She’s a real journalist now. Just not working with me. AARON PURI: No, it’s … And that’s something that we are trying to do in our independent lab now is use these as a resource for natural … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, … options. Note: In 2021, we conducted an extensive internal product audit to analyze the scientific value, demand, …

… . And then coming up after that, we’ll have a lineup of international scientists who also do genome mining. We’ve got a … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … biosynthetic gene clusters, which are the genes that do the biosynthesis of a secondary metabolite, those are clustered …

… fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental … single-cell profiling methods, including single-cell RNA-seq, single-cell ATAC-seq, and spatial transcriptomics … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working … But ultimately, they bought on. So now we have The Journal of Chemical Ecology that has a marine component. And …

… critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by … viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions. ISME J. … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … and biogeochemical cycles. Research Team    … A complete publication list available at Google Scholar. Schulz, C … symbiont infecting the nucleus of amoebae. The ISME Journal. 8 (8), 1634-1644 … Publications … For further details, …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … drug discovery has been a major driver for natural product biosynthesis. And probably a lot of the people and the …

Amazon ecology, [in] Portuguese, and got to do an independent study on ethnobotany of some of the plants that … And so I ended up as a postdoc Panama as part of the international cooperative biodiversity group (ICBG) based in … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much …

Yep. JACLYN WINTER: Yeah. And Paul had started his independent lab. And so there would– DAN UDWARY: Like Paul … with Bill Fenical at Scripps. So we’re looking at biosynthesis of marine fungal metabolites. We’re also … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … Eric for a long time – we worked together on Aflatoxin biosynthesis while he was a postdoc in Craig Townsend’s lab … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …