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… across at least two of the facilities, and generate datasets beyond what each of these facilities could generate … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … technologies available at JGI and EMSL such as DNA-SIP, Protein SIP, Flux Balance analysis with metabolites, Isotope …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… itself medicine, but the coding within the DNA codes for proteins that do the chemistry that put molecules together … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … a community effort of putting together the natural product structures that are known. I forget how many structures are …

… (meta)genomic, (meta)transcriptomic, and functional genomic data and serving them to users via the Integrated Microbial … specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within … distribution of microbial genome and microbiome datasets sequenced at the JGI. IMG/M is also open to scientists …

… a class of natural product with a really cool chemical structure. We try to explain it, but it’s chemistry, so I … very first compound was introduced in the early 90s and by using a polymer as a delivery mechanism. So, the polymer … So, we were essentially using brute force to isolate the proteins. The proteins are the biological version of the …

… also tackles challenges posed by environmental change, focusing on plant resilience — highlighting the vulnerabilities … including deep learning algorithms for gene annotation and protein folding models, to improve the accuracy of … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

… work as exploring and exploiting biocatalysts – that is, using enzymes to do chemical reactions. Obviously, in my … attraction to natural products was dual, the beauty of the structures and also the challenge and thinking about making … do engineering to improve the physical properties of a protein and make it easier to work with. But sometimes, what …

… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated … now uses laser microdissection to selectively isolate and sequence microbial aggregates after first imaging with …

So, I’ve always known Roger as an expert in natural product structure elucidation, but more recently, he’s been leading … from drug discovery in every possible disease target area, using an enormous array of different isolation strategies … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… has got to be new, or at least we hope. This is what we’re using to get funding, but. DAN UDWARY: Well, you’ve seen … Everything that we’re finding seems to be a new structure, and the microorganisms are novel. I mean, we have … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …