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Natural Prodcast Episode 10: A Primer on Genome Mining
… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … as seen on the phylogenetic tree, with new lineages of uncultivated genomes from the GEM catalog (in green) and …
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Plant-Microbial Interactions Group
… symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …
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Natural Prodcast Episode 23: Aaron Puri
… of genes. It was actually originally predicted to be a nonribosomal peptide synthetase but then flanked by these two … if you have a quorum sensing system or the genes that could encode for that right next to a larger biosynthetic gene … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …
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Natural Prodcast Episode 11: Marnix Medema
… of these crazy genes, some of these enormous genes that encode these very large enzymes. And I was like, OK, wow, … that end up being post-translationally modified into ribosomally synthesized peptide natural products. And they … sub domains”, where he made a big phylogeny of all the proteins that had the protein domain. And then for every …
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FICUS
… provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS …
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Natural Prodcast Episode 12: Nadine Ziemert
Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … links that they must be made in a certain way by these non-ribosomal peptide synthetases. Because they thought, at that … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure …
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University of California, Merced Internship Program
… 80 UC Merced students have contributed to the research of numerous JGI scientists. Interns say their experiences …
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Natural Prodcast Episode 19: Bill Fenical
… molecules that bound inside the cells to tubulin, these proteins that allow the cells to divide. We found all sorts … So of course, we decided, what are these? And we did the ribosomal taxonomic approach, looking at that, which allows you to compare the ribosomal gene, 16S gene, to all other bacteria known. And …
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Green Algae Reveal One mRNA Encodes Many Proteins
… – that is, a single gene makes messenger RNA, which encodes a single protein. Gene expression in eukaryotes was … – that is, a single gene makes messenger RNA, which encodes a single protein. Recently reported in the … Academy of Sciences , a team of researchers has found numerous examples of polycistronic expression – in which two …
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Natural Prodcast Episode 16: Marcy Balunas
And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … is it possible that these bacteria which are not incredibly numerous are protecting their eggs with these compounds? And … be able to find genes in the organism in its sequence that encode for that biosynthesis. But sometimes you have to know …
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Genome Insider
… to better understand — and harness — the superpowers encoded in plants, fungi, microalgae, environmental viruses, and bacteria to contribute to a more sustainable …
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Natural Prodcast Episode 13: Francisco Barona Goméz
… be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of … to find any new genomes, new areas or regions or loci, that encode for new, truly chemical dark matter BGCs. That’s the … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …
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