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… symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, … Selected Publications …
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… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … of a gene that you knew was probably biosynthetic that encoded for some secondary metabolism, then you would … what a polyketide synthase looks like. We know what a non-ribosomal peptide or a ribosomally processed peptide looks …
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… of genes. It was actually originally predicted to be a nonribosomal peptide synthetase but then flanked by these two … if you have a quorum sensing system or the genes that could encode for that right next to a larger biosynthetic gene … more structural diversity — so that one uses acyl carrier proteins as co-substrate. So the other ones they use CoA …
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… provides customized analysis, the JGI also participates in publication of results. …
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… of these crazy genes, some of these enormous genes that encode these very large enzymes. And I was like, OK, wow, … that end up being post-translationally modified into ribosomally synthesized peptide natural products. And they … sub domains”, where he made a big phylogeny of all the proteins that had the protein domain. And then for every …
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… resources and expertise. These collaborations have yielded numerous, high-quality outputs, such as data, publications and software. The JGI supports the entire data …
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… Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … links that they must be made in a certain way by these non-ribosomal peptide synthetases. Because they thought, at that … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure …
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… – that is, a single gene makes messenger RNA, which encodes a single protein. Gene expression in eukaryotes was … – that is, a single gene makes messenger RNA, which encodes a single protein. Recently reported in the … Academy of Sciences , a team of researchers has found numerous examples of polycistronic expression – in which two …
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… molecules that bound inside the cells to tubulin, these proteins that allow the cells to divide. We found all sorts … So of course, we decided, what are these? And we did the ribosomal taxonomic approach, looking at that, which allows you to compare the ribosomal gene, 16S gene, to all other bacteria known. And …
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… 90 UC Merced students have contributed to the research of numerous JGI scientists. Interns say their experiences …
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… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … is it possible that these bacteria which are not incredibly numerous are protecting their eggs with these compounds? And … be able to find genes in the organism in its sequence that encode for that biosynthesis. But sometimes you have to know …
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… waiting to be unearthed in sequencing and analyzing uncultivated microbes. Summary The CRISPR-Cas system is an … elements by incorporating short sequences from infecting viruses and phages. In the event of a new infection, the … Cas14 proteins on IMG/M portal …
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