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… sequences. As always, you’ll find transcripts and show notes with links to lots of other resources, especially … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … mining. So we’re here in California. And gold mining was a big endeavor. And I’m no expert, but the way that I …

… and have a great chat with him.  I kind of lost count of how many times Brad used the words “fun” and “magical” when … So we began to sequence that genome – it was a relatively small genome, about five and a half million base pairs. It … four double bonds in this one region of the molecule.  Dan: Big, complex molecule.  Brad: It was a complex chemical. …

… defense, nutrient acquisition and communication. Studying how these compounds are biosynthesized and their roles in the environment, can unlock new avenues for bio-based products and bioenergy … realized under standard laboratory conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being …

… them enough lately, but as always I have transcripts and show notes at naturalprodcast.com — I went a little overboard … living there. So we’re looking at how they adapt to these extreme environments. And then can we use that, for example, … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… ask the first question. Kate, can you tell me the story of how you got into secondary metabolites? Kate Duncan: So I … which is a great website name, and also extremely well-organized, makes doing research on a person … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… one of my favorite interviews so far – you’re going to hear how passionate and enthusiastic Ben is about our field, and … toxic molecules, and that human beings know, today, for small molecules. So they’re in the picomolar range. ALISON: … has acquired the Pfizer strain collection. And so that’s a big collection of natural product-producing organisms that …

… common tools that genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and … about today and it will be really good to maybe start with how did you get into this field? How did you get into … tiny precursor peptide, encoding genes that encode the very small precursor peptides that end up being …

… it. And just to remind you, you can get transcripts, and show notes with links to papers around the science we talked … the tetrapeptide, that's a 12 membered ring. And there's extreme ring strain in 12 membered rings. You also have to … Well, obviously, I teach, but the other thing that's been a big thing for me is thinking about mental health for …

… biosynthetic pathway, and I’ll have to do a whole show on it one of these days. If you listen to the Nancy … Right. So the zebras and the tigers and the charismatic big animals… They actually do have interesting chemistry, … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

Asked Questions about our proposal submission process. You can review successful letters of intent and submissions at … Generally, most users are able to work with Berkeley Lab.  However, users from certain countries (Iran, North Korea, … proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New …

… , and I’ll link out to everything in the show notes, as always, at naturalprodcast.com . And, if you … So these are some things that even if you’re not like a big pharma company and you’re just like an assistant … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as …

… part 2 of our “primer” episode, so if you ended up here somehow without having listened to the first part, you might be … yeah, so these guys, it turns out, produce lots of really small molecules that they use to communicate – lots of … top of this photograph, or one corner of it, you see this big white blob – sort of overexposed – but this this white …