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Experimental evolution of extremophile resistance to ionizing radiation
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Microbiome Data Science Team
Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …
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Natural Prodcast Episode 2: The Primer, Part 2
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … metabolism is based on primary metabolism. It’s an evolution of primary metabolism. So a lot of the genes and … Was it because were you already experiencing antibiotic resistance at that point?  DAN: Yeah, I’m glad you asked. …
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Natural Prodcast Episode 22: Alison Narayan
Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … make substitutions to test that hypothesis through site-directed mutagenesis, we would end up with dead enzymes. So … AU.  2023.   doi: 10.1021/jacsau.3c00263 “Deciphering the evolution of flavin-dependent monooxygenase …
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Institutional User Agreements
… starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …
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Microbial Program
… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … families, and pathways, enhancing our understanding of evolutionary diversification and microbial diversity. Learn … inferred host taxonomy, conjugation potential, antibiotic resistance genes, and ecosystem information. … The IMG/VR …
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Single Cell Research Group
Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … Biotechnol 35(8): 725-731 (2017). Woyke T . & Rubin E.M. Evolution. Searching for new branches on the tree of life. … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …
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Data Policy
Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to the following Data … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way …
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Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair
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Natural Prodcast Episode 16: Marcy Balunas
… know that that’s ever necessarily like a good description of anyone because chemistry means a lot, especially when … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … was episode 6.] about this. And really his focus was on the evolution of these systems and I understand you’ve worked on …
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Adaptive laboratory evolution for improved tolerance of isobutyl acetate in Escherichia coli
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How to Submit Sequencing Samples
Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting …
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