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… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … metabolism because a lot of secondary metabolism is horizontally transferred. Things shift between even … do some sort of slightly novel chemistry. That’s just how evolution works. So if secondary metabolism is really …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … JGI scientists are able to link metabolic activity with gene expression, providing deeper insights into functional …

… bright guy who’s been thinking for a long time about the evolution and natural products systems. This conversation … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

Genome Insider is a podcast that showcases the work of JGI collaborators in brief forays, connecting audiences with the people behind … — and harness — the superpowers encoded in plants, fungi, microalgae, environmental viruses, and bacteria to …

P. psychrophila genes drive resilience when salinity fluctuates. The Science The Arctic microalga … nutrient concentration and cell death. Immediately upon transfer, the experimental samples exhibited significant …

… see as the overall “theme” of your research? I know you’ve generally worked in various marine organisms. Except during … They’re at the base of the animal kingdom, in terms of evolution. Because they’re sitting there, they tend to have … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … types to explore the molecular mechanisms behind phenotypic evolution. It also utilizes advanced tools, including deep … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

And I found her review in natural product reports on the evolution of genome mining and microbes with Mohammad … of it. So it wasn’t only chemistry or only biochemistry or genetics. It was also ecology. It was also evolution. It was … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… what we’re calling a Primer. We wanted to try and give a general audience some of the basics of natural products … near this tree and so there was probably some historical evolutionary event where the DNA transferred from the fungus into the tree and became …

… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … we partnered with a company in Japan, Meiji Seika Pharma, transferred the technology that they developed over to Dow … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by … at improving our collective understanding of ecological and evolutionary parameters driving virus:host dynamics in … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … in more detail. Especially if you want to look at the evolution of these gene clusters, for example, you really …