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… fraction, AF) have been computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes based … ANI is used to ascertain the species specificity of single cells and genomes extracted from metagenomes, and also as a …

UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … doi: 10.1038/s41587-020-0718-6) The GEM catalog expands the bacterial and archaeal orders as seen on the phylogenetic …

… provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … Accessing Resources at Multiple DOE User Facilities with a Single Proposal describes the resources available from the …

… automation, and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics.   … Deputy …

… cluster with me because it turns out that oftentimes in bacterial genomes if you have a quorum sensing system or the … and they were able to synthesize the genes for every single one of those and put them in individual plasmids and … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … al. (2019) Minimum Information about an Uncultivated Virus Genome (MIUViG).  Nature Biotech .  37 , 29–37 Roux S, et … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… this identification, metabolomics enables functional genome annotation, improves understanding of the role small molecules play in …

… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … come, though, too when you start talking about going after single gene clusters. BRIAN BACHMANN: That’s right. JACKIE … mammalian systems. But it allows us to assay on a single cell level against cell lines and against primary cells …

BARONA-GOMEZ: Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a … we can really start testing and organizing things beyond artificial names. ALISON TAKEMURA: Just because I think I … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to …

… a great opportunity to learn more about JGI, hear some excellent talk from our users and from other invited guests, … and the stabilized isotope probing work that we’re doing, single cell work we’re doing. And using these together along … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

Integrated Microbial Genomics at JGI, a large data set of bacterial genomes. And so yeah, we use antiSMASH to identify … sometimes correlated or anti correlated, also with other cellular functions in the same and as it was other bacteria … structure activity relationships using machine learning and artificial intelligence. I think there is a lot of things …