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… proposal call . This represents a unique opportunity for researchers to request the capabilities and expertise of … science, accelerating discoveries and developing transformative bio-based technologies that address challenges in … capabilities, they then ship samples—such as DNA and RNA for sequencing—to JGI. Users are responsible for covering …

… engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data … discoverability and accessibility are critical requirements for amplifying the JGI’s impact. Data generated from a single investment will be reused for further science.  Notices Data Portal files will be …

… episodes has sparked your interest, and you want to learn more, then I highly recommend David Hopwood’s book called  … lots of new molecules being discovered lots of new things making it to market and they wanted to keep that trend the … long process of natural products-based discovery. Not the case, as you say, not too many new drugs making it to …

… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with … insights from sequence data, employing IMG data and tools for comparative analysis, visualization and interpretation …

… staff in the Integrative Genomics Building in Berkeley, California.  Our location at the IGB fosters team science and … biotechnology through analyzing and harnessing genomic information from plants, fungi, algae, non-medical microbes, … of four partner institutions: Berkeley Lab, Lawrence Livermore National Laboratory , the HudsonAlpha Institute for …

… Takemura, whose voice you’ll hear in a minute – we work for the US Department of Energy Joint Genome Institute, or … even though the science in that Facebook post is probably more than a little fuzzy. The natural products – or … you can smell it. That fresh dirt smell: that is bacteria making natural products  ALISON: Hmm. It kind of – it’s kind …

… discovery at the DOE Office of Science through high performance computing (HPC) and data analysis.  The DOE Systems … function.   To jointly support these missions, and to expand upon highly successful past collaborations, the DOE JGI, NERSC and KBase issued a call for proposals in biological data science as part of the …

… And as I was doing my chemistry work I really became more and more interested in cancer drug discovery and … over about a month.  DAN: What are those bacteria making?  MARCY: What are those– they make chemistry! And so … is in liquid culture, and we have a co-culture in this case would be that we have a culture of the bacterium …

… Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … diversity and metabolic potential, with implications for energy production, environmental sustainability, and … linked to custom interfaces and visualization tools for user analysis. Additionally, the Program works to link …

… right? I mean, at the end, we somehow have the big goal of making that process a little more effective than it is now. Or a little more– yeah, put … differently. ALISON TAKEMURA: For that example, was it the case where that colleague saw a potential mechanism for why …

… and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, archaea, they all have … so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this … within, say, the sponges or other things. And we know lots more about microbiomes and symbionts that live with other …

… this description, but I’d say that Alison is not one of the more normal kinds of natural products people we usually talk … of the structures and also the challenge and thinking about making them. So I really came at it not necessarily based on … heard that before. Why is that? Why would that be the case? ALISON NARAYAN: It’s a great question. If you dive …