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… flowing– water flows into them and floods them on a regular basis. So they are full of terrestrial microbes. So they’re … to the genome mining-based approaches are that other than resistance genes, you have no way of knowing of whether or … we’re targeting what we think are privileged classes of molecular diversity and then plugging that into these …

… product hits. Sort of in parallel with that, the field of molecular biology got more sophisticated around the 80s and … to RNA to protein. DAN: Yeah, this is the central dogma of molecular biology. And so DNA makes RNA makes protein. … maybe, people who are less familiar with central dogmas of molecular biology, DNA is the storage medium for information …

… is by comparison. We’ll talk about that when we talk about molecular biology.  But um, yeah, so secondary metabolism is … Was it because were you already experiencing antibiotic resistance at that point?  DAN: Yeah, I’m glad you asked. … about the use of antibiotics is that eventually, antibiotic resistance is going to set in. The more you use an …

… types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes … metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et al. …

… and storage (from PacBio) Best practices for High Molecular Weight DNA extraction and quality control (from …

… and Operations teams to enable the JGI’s focus on expanding molecular capabilities and functional genomics, scaling …

… at Oak Ridge National Laboratory  Center for Structural Molecular Biology . …

…   Overview of metabolomics products At JGI, in-depth molecular profiles are generated for metabolites extracted …

… in. And there is quite a bit of sun and exposure to solar radiation with refraction through the ice.  DAN: What’s your …

… fungi were transformed. So I wasn’t even thinking of molecular genetics of finding genes when I first started … And it’s actually been pretty easy to breed plants with resistance to pathogenic fungi that invade or colonize their … plant. It’s us that eats the plant. So how do you breed for resistance to a compound that, with the exception of maybe …