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… was a golden age right there when we were all in the lab together and the ring tank party. But that’s when a bunch of … by submitting it, you are checking a box and agreeing to making that data public. So yeah. So if you don’t want your … boats because anytime somebody is working on something or making some posts or whatever that becomes public and …
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… maybe this is a safe place to grow because we’re all here together. ALISON: How beautiful. What a great partnership. … a long time. But… DAN: Yeah, there are a lot of ways to put together carbon molecules. Chemistry is pretty limitless. … But these kinds of bacteria grow in filaments and they grow together in clumps, almost like, you know, like an organism. …
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… right? I mean, at the end, we somehow have the big goal of making that process a little more effective than it is now. … went to Scripps [Institution of Oceanography in San Diego] together. And I worked for Brad Moore as a postdoc and you … a lot of searching the internet, searching literature, and making databases. Because that’s what I noticed is really a …
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… six episodes, and now after gathering some feedback and making a few technical tweaks, I think we’ll be on a pretty … united by natural products, DAN: You guys have put together a fantastic program. So I’m looking forward to the … you’re asking the question why in nature are you making only one of the two hands. So that’s a question about …
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… want to say thank you, personally, to everyone involved in making this happen. We had a really fun conversation with … Oceanography]. ROGER: Yeah, that’s right. We were postdocs together in the mid 2000s, I guess. You were working for … might be more to be gained than just subject matter, by making that change. So I went to the University of British …
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… heard a little about these, and Aaron and JGI are working together to try to understand the enzymology of their … the anaerobic ecosystem. And you have some oxygen that is making its way down. And in that Goldilocks zone is where … behaviors. And so immediately you know like I said, we’re making all of these hypotheses or you’re fantasizing about …
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… new company called Corteva, bringing these two businesses together. And so I’d reached this time when I thought, well, … we’re doing, single cell work we’re doing. And using these together along with all of our computational tools to really … And so I think this is really cool technology now that is making up a lot of our expression platform work. And I think …
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… And so, I was working on chemically synthesizing and making derivatives of this to test its anticancer agent … cluster and a gene cluster for natural product might be all together. And so that's how we decide what we're going to … this journey, is finding these enzymes that are capable of making those strange ring systems. JACKIE: Why? Is it just …
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… codes for proteins that do the chemistry that put molecules together that become bioactive molecules in some cases, … biosynthesis of a secondary metabolite, those are clustered together in a genome for some reason. So if you could find a … mining, how the biosynthetic gene clusters are clustered together so it can be easy to find the whole pathway. So how …
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… excited. This is the first time we’ve recorded something together. So, this is fun. MENAKA WILHELM: Yeah, it’s true. … And so I don’t know. I thought it’d be fun for us to work together to talk about this kind of stuff and talk to a few … team up with somebody who can do that. And then the team together makes a really strong proposal and a strong …
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… list of things. So we have a Scripps background shared together, although I don’t think we overlapped. Kate Duncan: … or antibiotics and stuff like that. Dan Udwary: Yeah, making biofuels has to be really cost-efficient or you have … I’m talking of CEOs, professors, and the kind of decision making table– the data is still very unequal. Dan Udwary: …
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