Search

… cluster the products of the biosynthetic gene cluster is regulated. DAN: By the quorum sensing system. Yeah. AARON … could imagine if you have two colonies of bacteria in the soil or something and they’re competing with each other, if … ecology community to be able to better predict how their microbes are interacting with each other from sequence …

… was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods was these damn … for antibiotics and the microbes that make them is in the soil. There’s … uh… there’s an issue there though, in that … to go in the next couple years. And hopefully, some of the insights that we glean from that will be broadly applicable …

… NIGEL MOUNCEY: Yeah. And the ag industry is highly regulated and that drives a lot of the timeline.  DAN: Yeah, … But they really span our core science programs which are microbes, and fungi, and algae plants, synthetic biology. …

… effort, researchers have identified a protein in soil viruses that may promote soil health. The work was … only to cellulose.  Chitin is also a common food source for microbes living within soil. So, the chitosanase protein … X-rays.  This study only begins to unearth the insights to be found within soil viruses and AMGs. It could …

… we really recognize, right?  ALISON: And I tend to think of microbes as being able to secrete a lot more things than … But… DAN: Yeah, there are a lot of ways to put together carbon molecules. Chemistry is pretty limitless. All right, … products because they’re easy to find. They grow in the soil. These are the same guys that produce geosmin. And so …

… variety of experimental samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types of environments (e.g. soil, lake).  A wide range of metabolites are identified …

… means to begin filling this gap. A primary goal is to get  insights into the coding potential of candidate phyla  to … Stepanauskas R., Rubin E.M., Hugenholtz P. & Woyke T . Insights into the phylogeny and coding potential of … Bergin C., Ruehland C., Rubin E.M. & Dubilier, N. Symbiosis insights through metagenomic analysis of a microbial …

… was adjacent to what I worked on, but my experience of how microbes are interacting in the environment like, like my … Institution of Oceanography. He got me into genomics of microbes, specifically of some that lived in the ocean and … is a chemical compound called geosmin that’s produced by soil bacteria that live all over the place. So that smell of …

… and work within the DOE emission space of bioenergy, carbon cycling, biogeochemistry, bioproducts. So we cannot … where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a high … and coastal. But we’ve kind of shied away from the ocean. Microbes. We’ve done those in the past, but the DOE mission …

… sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling strategies that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic … activity (BONCAT+FACS). To provide additional functional insights into microbial genomes, the JGI now uses laser …