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New Lineages of Life Group
… Our research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … to identify new divergent lineages and expand the Tree of Life. We then investigate the coding potential to find … Exploring the fascinating world of giant viruses, which challenge our understanding of viral …
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Mission
… JGI Mission As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic capabilities, large-scale AI-ready data and professional expertise to support the global research community in … and manufacturing. Genomic science lies at the heart of biology, providing the foundational knowledge to …
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Natural Prodcast Episode 5: Brad Moore
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  Brad Moore, UC San Diego and Scripps … chemist, Richard Moore, and get into seaweed, robots, algae, and biocatalysis — and he makes fun of me a lot, …
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Strain Engineering
… The focus of this group, in recent years, has been to bring generalizable technologies to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and functional exploration.  The developed strains … For further details, please reach out to the Group Lead …
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Frequently Asked Questions: Project Management
… Tijana Glavina del Rio , Danielle Graham , or Miranda Harmon-Smith DNA Synthesis projects: Miranda Harmon-Smith Metabolomics projects: Christa Pennacchio   … You can visit the Products & Offerings section of our website for more details, including a downloadable …
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Institutional User Agreements
… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of … After your proposal is approved, the Contracts Officer will send required paperwork to your … to DNA Synthesis proposals from PIs at other DOE National Labs …
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Metabolomics
… JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this identification, … functional genome annotation, improves understanding of the role small molecules play in diverse biological … Find more details on the instrumentation we use and our methodology for …
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JGI@25: The Little Alga That Could
… In honor of the JGI's 25th anniversary in 2022, we have … to those who study it) a powerful reference organism for studying photosynthesis and cell motility. It’s also a model for studying lipid production in other algae that may be more viable for sustainable biofuel …
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How to Submit Sequencing Samples
… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting … at the JGI. The quality of the starting material is one of the greatest predictors of a successful sequencing …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… fluctuates. The Science The Arctic microalga Plocamiomonas psychrophila can thrive in changing conditions. A … were able to identify specific genes that allow the algae to adapt to sudden drops in salt levels, enabling it … ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … In this episode, Dan and Alison discuss the basics of genome mining, as we get ready to talk to some of the …
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Products
… in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway engineering Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … to completion of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will …
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