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… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, advancing the development of … the program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal … single cell approaches. This includes linking strain-level genetic variation to ecological niche adaptations.  Single …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … to identify new divergent lineages and expand the Tree of Life. We then investigate the coding potential to find novel functions that may impact microbiome structure and biogeochemical cycles. Research …

… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, … Elucidating Sphagnum microbiome genetic interactions for improved growth at … strategies in a cosmopolitan and abundant soil bacterium: genetic microdiversity or core metabolic flexibility? …

… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, … access to diverse datasets that deepen our understanding of how organisms interact with each other and with their …

… The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new … The JGI uniquely offers the first quantitative Stable Isotope Probing (SIP) … analytical standards to accurately measure environmental microbiome activity levels.This functional assay lets us …

… Guiding Principles All staff members of the US Department of Energy (DOE) Joint Genome Institute (JGI) commit to … and JGI staff with respect and consideration, valuing a diversity of views and opinions; Exercise tolerance for …

… Maize produces a family of compounds that protects it … enzymes. The Science Maize ( Zea mays ) produces a plethora of antibiotics called zealexins. Even though scientists have … They screened panels of hundreds of maize lines for genetic variation in the ability make zealexins, and …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … is that you could, therefore, expect a lot of chemical diversity. So many compounds will fulfill the same function. … So we had a series of criteria to say this is a bunch of genetic material that exists in one copy, and it is …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … rich and underappreciated. And we’ve worked both with the microbiome. So, with symbiotic bacteria that live in animals … with animal metabolism itself, and it’s really amazing what diversity there is in animals. I think, even despite the …

… work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided … by the Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or published.  The purpose of the program is to: Build curiosity and illustrate the …