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… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … the in the 50s 60s 70s, most of the exploration of this is done by what’s called “find and grind”. So you would find … be useful. And so that was great for a while, but it’s not everything. So, finding new sources is somewhat …

The Metagenome Program uses advanced sequencing technologies to … such as carbon cycling, nutrient cycling, and energy flow. One of the key goals of the Program is to develop a deeper … as a community resource for comparative analysis and annotation of all publicly available genomes from three …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on … department at the University of Utah, so that makes him one of Jackie’s colleagues. Aaron is doing some cool stuff … And it actually was jumping onto the I ntegrated Microbial Genomes and Metagenomes, the IMG platform that JGI has that …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … suggest you go back and check the first episode out. This one continues the introductory conversation between myself … of natural products and the state of the field today. So, not as much of a preamble this time. Let’s jump right in. — …

… … DAN UDWARY: Hey, everyone! Welcome to the “Self Promotion Episode” of Natural … one that wanted to get out there as soon as possible. Not one of our normal interviews, but instead it’s two … Breaking Bad, I guess. But no, you trained me in how to genome mine, so thank you for that. And you had to put up …

… small genes assembled to less than 5kb in length, cloned into vector of choice Glycerol stock of sequence … Fungal Minimal Draft Lower coverage short-read whole genome shotgun sequencing Assembly, annotation ( Mycocosm ) … For counting: text file of gene counts (mapped against reference transcriptome or de novo assembly), DGE, alignment …

So I always liked science in school. I wouldn’t say I was one of these people that wants to study oceanography and was … incredibly enthusiastic and gave me a bunch of books, but not books on marine natural products, as such, but things … was really before– or kind of around about when the first genome sequencing was done. But natural products– marine …

… they can modulate host metabolism, gene expression and phenotype. We have recently identified resident bacteriophages … rhizobacterium (PGPR) Pseudomonas simiae WCS417. One suggested function of these phage genes is the … single-cell atlas comprising Sorghum, Switchgrass, and Brachypodium datasets. We recently profiled the association …

Am fine. I live in a pandemic so I’m no different than anyone else.  DAN: Yeah. I mean fine in pandemic adjusted terms … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … of her work on molluscs and their cyanobacterial feeding preferences A 10″ Simple Rules” article on increasing …

… “Adopt a Genome” is an informal program for faculty to “claim” the … genomes that have been sequenced by the JGI though not formally analyzed or published.  The purpose of the … working with the JGI 120 genomes claimed (or about one per student) Seven student-drafted articles accepted …

… , and I’ll link out to everything in the show notes, as always, at naturalprodcast.com . And, if you can’t … circles in some way or another. But today, we have someone who, weirdly, I haven’t, I think, ever been in a room … it’s not that easy. There are still not that many plant genomes, certainly nowhere close to bacterial kinds of …

… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the … got the chance to record this conversation. I also want to note that this episode will be monumental as the last … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …