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Sequencing Technologies & Products
…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust offering of … through end-to-end automation — and further advancing sequence applications, single cell genomics, biodesign, and … An assay used for profiling transcription factor binding sites across entire …
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New Lineages of Life Group
… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … Exploring the fascinating world of giant viruses, which challenge our … Understanding the complex relationships between microbes and eukaryotes and their impact on ecosystem …
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Sequencing Submission Requirements for DNA Synthesis
… When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  Miranda Harmon-Smith, Synthetic Biology Project … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …
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How to Submit Sequencing Samples
… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on accessing sample-level reports and … 1) Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been …
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Natural Prodcast Episode 1: The Primer, Part 1
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … was adjacent to what I worked on, but my experience of how microbes are interacting in the environment like, like my …
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Natural Prodcast Episode 12: Nadine Ziemert
… product reports on the evolution of genome mining and microbes with Mohammad Alanjary and Tilmann Weber to be a … there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … fun that we've started that is a different subject is from microbes to medicine labs. So this is-- we've been working …
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Natural Prodcast Episode 13: Francisco Barona Goméz
… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … At the end of the day, all the content produced by microbes the result of millions of years of evolution. And … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …
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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a high-throughput AI-centric … genomic information from plants, fungi, algae, non-medical microbes, microbial communities, and other relevant …
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Natural Prodcast Episode 2: The Primer, Part 2
… we really recognize, right?  ALISON: And I tend to think of microbes as being able to secrete a lot more things than … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but this is an important one that … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …
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