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Bacillus spores for a long time for food spoilage kind of testing, applications. And that’s funny because I – later on … then to partner up with people that might be interested in testing these in a range of applications.  We’re not going … team who have been really looking at ways to express genes in organisms that haven’t been used for really any …

… metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … and a list of scored metabolite matches associated with genes.  … Metabolomics Offerings & Capabilities … …

… coelicolor versus Streptomyces lividans. They both have the genes. The genes are pretty much 100% identical. We don't … we can activate these, utilizing some of these already synthesized molecules. DAN: OK. These receptors are coming … inspired molecules that you have, what assays are you testing them in? Because a lot of these compounds are really …

… to process optimization and development approaches, testing various platforms to see what works best for …

… aflatoxin being a secondary metabolite from an Aspergillus species that is pretty toxic – can cause liver … with. So transformation, or manipulation of the DNA of genes and bacteria, occurred much faster earlier than they … So I wasn’t even thinking of molecular genetics of finding genes when I first started out, because that wasn’t on the …

… cutting-edge research in synthetic biology by synthesizing genes, pathways, and whole chromosomes for bioenergy and … construct variations. These constructs are subsequently synthesized and tested for their ability to produce desired … Plant Comparative Genomics portal. Families of related genes representing the modern descendants of ancestral genes …

… in most fungi, biosynthetic gene clusters, which are the genes that do the biosynthesis of a secondary metabolite, … way, where we had– aflatoxin is produced by a fungus called Aspergillus . We were mostly working in Aspergillus … cluster makes a product and how a product should be synthesized based on its structure, that we should be able …

… and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … organisms? Can you manipulate them? Or can you move the genes and heterologously express them? Is there like a great host that you could use if you can’t knock genes out? AARON PURI: Yeah. It’s a great question. So that …