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The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … to address some of the world’s most pressing challenges. … Exploration of phylogenomic novelty: Advances in metagenomic …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any … of collaborators and users. For example if, by agreement with the collaborator, JGI staff take a lead role in the …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … pathways. And today, we get to present our conversation with Marnix Medema , from Wageningen University in the … primer episode, we talked about genome mining through some metagenome associated genomes. And yes, antiSMASH is …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided … datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes (MAGs), and 40,000+ metagenomes …

…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … to tap into the largely unexplored biochemical diversity within secondary metabolites, expanding their potential …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … focus on microbiome research.  These efforts include exploration of the global diversity of alternative genetic … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … on our Genomic Encyclopedia of Bacteria and Archaea . Exploration of inter-organismal interactions: In an effort … capability of microbial communities based on their metagenome sequence, in the context of reference isolate …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … of their bacterial host to colonize plant roots, as with Arabidopsis thaliana. Using a coupled experimental and … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome … of novel metabolites, genes, and proteins. It also enables exploration of energy and nutrient exchange, as well as …

… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … diversity for these species. The pangenomes enable the exploration and identification of small and large structural … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

… assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, nutrient cycling and … automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables … length  Pooled libraries such as sgRNA, promoter or MoClo assemblies … Check out our organism-agnostic CRISPR gRNA …