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Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We revisited a number of notable … and environmental challenges.  Commissioned for the JGI’s 25th anniversary, the JGI mural references dozens of iconic …

… getting them out to you all. But for now, here is episode 10 of Natural Prodcast, the primer on genome mining. Hey, … in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… of protective tricks. Nature Reviews Microbiology 20 (5), 255-255 Schulz et al. (2020) Giant virus diversity and host … binning of a giant virus. mSystems. 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature … in the Gammaproteobacteria. Scientific reports. 5 (1), 1-10 Schulz et al. (2014) Life in an unusual intracellular …

And you have these different types of particulate like 2.5, 10 PPMs and just the size of the particle and how far they … there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re trying to do …

… al.  2023 . Microbiology Resource Announcements. 2023 12 (10), e00548-23 Whole genome sequence of the denitrifying … Draft genome sequences of  Butyrivibrio hungatei  DSM 14810 (JK 615T) and  Butyrivibrio fibrisolvens DSM 3071 (D1T).  … Pouch of a Diseased Male Seahorse. E. Bond, et. al.  2025. Microbiol Resour Announc. 2025 Draft Genome Sequence of  …

… to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on … that you do, then it’s very easy to think that, OK, I find 25 gene clusters, there must be 25 new compounds. Or …

The two-story JGI mural was commissioned for the JGI’s 25th anniversary and done by Berkeley-based artist Nigel …

So they’re in the picomolar range. ALISON: Picomole… is [10 to the] minus twelve, right? BEN: Yeah, yeah. Well, we … company Wyeth that introduced enediynes to the market in 2001 with a drug called Mylotag. Wyeth was later acquired by … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain …

… so there are– I hesitate to make a guess but maybe 50 to 100 different strains and they are in individual tubules.  … say a clutch is probably the size of a golf ball and has 25 to 50 eggs. I’m guessing here.  DAN: Sure, sure.  MARCY: … in the field, these glacial bacteria grow slow and it’s not 100% clear that we know what their biological activities …

… convince those people of that fact, however, a long time, 10 years! ALISON TAKEMURA: Wow. It’s all happened so fast. I … of the molecules in ecology. And that took another 10 years at least. But I had several students. And I worked … chemistry. And I’ve studied microbiology for about 25, 30 years. And I can actually go give a talk at ASM [The …

… because I was always swimming or surfing. And you know, 25 hours a day we’re at the beach practically. It was just – … pairs. It was not linear, like Streptomyces , but circular. 10% of the genome encoded natural product pathways. Dan: … has been a lot of fun for us in recent years. Started in 2015, when two things happened. One, a new graduate student …