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… welcome back to Natural Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In … talk and that now I can bring it to you. So enjoy, episode 11 of Natural Prodcast. Alison Takemura: Marnix, where are … to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on …

… there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and …

… this is Challis et al, Chemistry and Biology, 2000, 211-224, 7:3 And so, you can then make predictions about … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… into DNA by active microbial populations (Hungate et al. 2015). With the development of high-throughput SIP (Nuccio et … strategies across environmental microbiomes. mSystems0:e01744-24. https://doi.org/10.1128/msystems.01744-24 Oliver, T., Varghese, N., Roux, S. et …

… from metagenomes. mSystems 9:e00888-24. https://doi.org/10.1128/msystems.00888-24 Coclet, C., Sorensen, P.O., Karaoz, … in a high-altitude watershed soil ecosystem. Microbiome 11, 237. https://doi.org/10.1186/s40168-023-01666-z Neri U., Wolf, Y., Roux S., Camargo A.P., …

… modules Currently 206 genomes have been selected with 11 published manuscripts published to-date Testimonials: … Resour Announc 0:e00891-25. https://doi.org/10.1128/mra.00891-25 . B. Christenson, I. Nouioui, C. Daum, M. … blood in Cleveland, Ohio. Microbiol Resour Announc. 0:e01296-24. https://doi.org/10.1128/mra.01296-24 V. Torres, R. …

… company Wyeth that introduced enediynes to the market in 2001 with a drug called Mylotag. Wyeth was later acquired by … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … look at several natural product enediyne structures, Ben’s 2015 paper on genome mining for enediynes is one of my …

… never forced it on me, but we always had these scientific news magazines lying around at home. And I would just pick … NIGEL MOUNCEY: Yeah, so we put out a strategic plan in 2018. And in building that plan, we thought about secondary … Metabolites Science Program . Since his arrival in 2017, Nigel has led a vision for the JGI that sees secondary …

… then my lab pleaded mercy, and I said, OK, we’ll just do 2011 to present day. And it was still like 4,000 articles we … plants and bringing them back is not your jam, the good news is there’s this amazing resource that can be provided …