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The JGI has a strong interest in seeing that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … from such efforts should specify the collaborative nature of the project, and authorship is expected to include …

… the answer would be that there’s actually a great deal of diversity within these methanotrophs for example, that are … for every single one of those and put them in individual plasmids and put those plasmids in E. coli . We were then … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… then, chemistry-wise, they’re the stars, right? Chemical diversity, the sheer number of chemicals they produce, their … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to … nutrients, and media, that there’s a good tip, or certain plasmids that are– so it was a bit of capturing all this …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … Yeah, bacteria sound like a good place, to me, to look for diversity because there are so many bacteria, because it is …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … with animal metabolism itself, and it’s really amazing what diversity there is in animals. I think, even despite the … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … is that you could, therefore, expect a lot of chemical diversity. So many compounds will fulfill the same function. … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. How are you?  MARCY: Am fine. I live in a … postdoc Panama as part of the international cooperative biodiversity group (ICBG) based in Panama and was dual there … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much …

… right. Welcome back to Natural Prodcast. I did it. I’m keeping to my schedule. This should be coming out on the first … And once we figure that out, we have designed GFP based plasmids where we can actually then put these in E. coli and … DAN: Oh, I did not know that. That's cool. JACKIE: But nature can do this. BETSY PARKINSON: But nature can do it …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … was less nutrients but enough that you had a lot of biodiversity. So we choose environments that are close enough … to this? Or you’re just really like– molecular biology on plasmids and stuff to express things, or? What’s the– BRIAN …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … fundamentals. What is beautiful for natural products is nature! Nature does this sort of – if you think of nature as … you to, say, go to your grandma’s backyard. To collect the diversity that exists in the 1940s? The answer is no! If …

… of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but this is an important one that … we sequenced the genome. And it has 17 resistant genes on a plasmid that’s actually– it’s pretty scary what this thing … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …