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… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … facility, provided this is done in a timely fashion. The publications resulting from such efforts should specify the …

… as exploring and exploiting biocatalysts – that is, using enzymes to do chemical reactions. Obviously, in my work, in … interesting. ALISON NARAYAN: It is a result that has a functional benefit for us, being chemists working with … off– JACKIE WINTER: No. ALISON NARAYAN: Often, they’re abbreviated too from alpha ketoglutarate to just AKGs. In my lab, …

… by bacterial or fungal metabolism by microbes, will have a functional role. We started from that. Evolution doesn’t … will be very flexible. They will allow promiscuity and the enzymes are driving the production of these compounds, which, in turn, translate into a high chemical diversity. So that’s just the type of …

… as an undergraduate, I was like, no, I’m going to study architecture. I like making things and designing things. I’m … two sequenced genomes of a Streptomyces , or gram-positive high GC organism.  Dan: Yeah, not a lot of natural product … might make this molecule and predicting what kind of enzymes might be involved, and then being able to make those …

… solutions.  The program has been a pioneering effort in functional genomics since 2012, with a focus on addressing … The DNA Synthesis Program plays a central role in advancing functional genomics, focusing on developing genetic systems … tools that enhance biofuel production and biosystem design. High-throughput design and synthesis capabilities accelerate …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … analysis. Importantly, IMG/M provides data and tools via a graphical user interface, so no programming knowledge … Publications … research experience "light" and... they're getting a publication at the end. " — Professor Matt Escobar,  CSU San …

… of microbial ecology and metabolism by elucidating the functional potential of hard-to-culture microorganisms. This … monitoring, bioremediation, and the discovery of novel enzymes and bioactive compounds. … populations (Hungate et al. 2015). With the development of high-throughput SIP (Nuccio et al. 2022) and terabase-scale …

… felt kind of like training for a marathon by running at a high altitude! And a lot of us moved on to work in simpler … the “Non-Ribosomal Peptide Synthetases” or NRPSs. These are enzyme systems that grab amino acids and stick them together … You know, unbeknownst to us beforehand, it was made via this ribosomal peptide type of pathway. So that brought …

… of host-virus interactions, the exploration of the functional dark matter as well as the development of novel … Pavlopoulos GA et al. (2023) Unraveling the functional dark matter through global metagenomics. Nature . … (2018) Programmed DNA destruction by miniature CRISPR-Cas14 enzymes. Science 362(6416):839-842. Duerkop BA, et al. …

… including especially metatranscriptomics, to better highlight and ultimately predict the main viral impacts in … different approaches including laboratory incubations and microfluidics methods to better investigate the host range … prediction for uncultivated phages improved annotation and functional prediction for phage proteins user-friendly …