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The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in … and activity in natural environments. Integrating metatranscriptomes and metagenomes can, for instance, …

Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …

… of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level … capability of microbial communities based on their metagenome sequence, in the context of reference isolate … automatically identified from genomes, metagenomes, and metatranscriptomes. It provides rich data such as inferred …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts …

ANI is used to ascertain the species specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …

… al. (2021) CheckV assesses the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . … Bowers RM, et al. (2017) Minimum information about a single amplified genome (MISAG) and a metagenome-assembled … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes (MAGs), and 40,000+ metagenomes …

… percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than … metabolites and unidentified features in spectra. 167/214 Metagenome Metatranscriptome Environmental transcript sequence …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … genomics-powered tools to study this complexity, including single-cell and spatial transcriptomics barcode-based … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way … PI and receive permission for their planned work.   … For sequencing or metabolomics projects: data are subject to a  … to the 2-year use-restriction policy as described here. No single project has data under both use-restriction and …