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… topic in, arguably, my area of expertise, which is genome mining. You’ll hear us talk about what it is, hear me make a … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … streams. This will all become clearer as we get into the genomics. So– ALISON TAKEMURA: I’m just enjoying the ride …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the … interpretation of sequence, metabolomics, and functional genomics data types as well as in advanced assembly and …

I think the important thing to remember is that, thanks to genomics, we now know that it is very hard to find stuff … not an easy one. DAN UDWARY: And how does this relate to EvoMining? FRANCISCO BARONA-GOMEZ: OK so the EvoMining idea … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural product … mechanistic enzymology to natural product biosynthesis to genomics to directed evolution– but it’s just the– it really …

… be episode 11. This continues our little sprint on genome mining. In the last episode , Alison and I talked about the … genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … of hooks into IMG’s data. IMG being Integrated Microbial Genomics at JGI, a large data set of bacterial genomes. And …

… in natural product reports on the evolution of genome mining and microbes with Mohammad Alanjary and Tilmann Weber … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … I think GTDB also started that. But I think taxonomy and genomic data are still kind of a mess. DAN UDWARY: Yeah, …

… the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural … as exploring and exploiting biocatalysts – that is, using enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us genome …

… vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and … and biogeochemistry. This research helps translate their genomic potential into practical applications, including … and ecological diversity of fungi and algae, examining both natural populations and engineered strains. This …

… bioenergy solutions.  The program has been a pioneering effort in functional genomics since 2012, with a focus on addressing critical … vision for a sustainable, bio-based economy. … Genome to Enzymes and Pathways focuses on discovering and …

The CSP Functional Genomics call is to enable users to perform …

… about what are they doing. And so it’s really functional genomics. And there’s a lot of sequencing based approaches, … our computational tools to really build out much more of an integrative genomics approach to studying environments, … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… not good at that, you guys. I’m trying really hard just for you. And the JGI Comms team. But mostly you. Anyway…I’m … to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of entomology … is you will mix together your receptor of interest with genomic DNA, and then allow that to bind. Your receptor also …