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Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …

… by environmental change, focusing on plant resilience — highlighting the vulnerabilities of monocultures and the … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of … high-quality de novo assemblies for very large-scale single genomes, based on the JGI assembly tool meraculous. …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any … of sequence, metabolomics, and functional genomics data types as well as in advanced assembly and engineering …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … genomics-powered tools to study this complexity, including single-cell and spatial transcriptomics barcode-based … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

… percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than … Assembly, annotation ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments Obtained by physical separation of a … ( IMG ) 280/298 Microbial Improved Draft, Isolate High quality draft assembly of long-read sequence data, …

Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of … technology in order to enhance the quality of single-cell genomes and directly link functional information with …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … DAN: Yeah, I don’t think your lab is gonna tackle that single handedly, right? So, yeah, getting the community …

We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … and biogeochemical cycles. Research Team    … A complete publication list available at Google Scholar. Schulz, C …

… challenge is, as the listeners know, even when you find a highly potent active compound that has a good cytotoxicity … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … screen, I think having assays that are amenable to – high-throughput testing is really important for us. In this …

The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With advanced mass … terrestrial biogeochemical processes, development of high performance plants and microbes, and understanding …

… research proposal.  Successful applications will focus on high-risk/high-payoff proposals within the focused topic … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … Accessing Resources at Multiple DOE User Facilities with a Single Proposal describes the resources available from the …