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… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the … acknowledgment (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, …

… conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … expression platforms, tools and data for deciphering regulatory networks, and refining experimental approaches to explore …

… the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … the feeling, we have is that if you have in these molecular networks, nodes that are not so highly diversified, for … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s unpublished … faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … while nurturing a fresh cohort of users Reach the next generation of genome scientists and recruit new talent for …

… sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  … and 200 polar/500 nonpolar metabolomics samples, and should generally conform to the guidelines for our  CSP Large Scale … also study ways to develop valuable byproducts from lignin left over after biomass processing. Great Lakes …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … biogeochemical processes, development of high performance plants and microbes, and understanding microbiome …

… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m … and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. Dan … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to … at all that space in the data of– if you look at molecular networks and how much is characterized and how much is …

… not good at that, you guys. I’m trying really hard just for you. And the JGI Comms team. But mostly you. Anyway…I’m … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … our audience, so the goal here then is to understand these regulatory mechanisms so that you can turn on the natural …

… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … around it, so you would actually be able to navigate these networks very easily. Also in an HTML format, which is also …