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… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … of microbial metabolism towards a minority of cultivated bacteria, still persists to date. Research Team    … In particular during an era of ‘homology creep’, function prediction as purely based on annotation may not be …

… the JGI’s focus on expanding molecular capabilities and functional genomics, scaling capacity through end-to-end … automation — and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics … offers quantitative Stable Isotope Probing (SIP) Metagenomics to the broader scientific community. The pipeline …

… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … are being explored to predict microbial lifestyles using AI-driven analysis of such datasets. The program also … applications. By expanding our knowledge of microbial functions and interactions, the Microbial Program supports …

… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they … constraints exerted by viruses. Research in the viral genomics group aims at improving our collective … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … We then investigate the coding potential to find novel functions that may impact microbiome structure and … possess genomes and particle sizes that rival those of cellular organisms. Giant viruses challenge the traditional …

… in their natural environments. This work encompasses bacteria, archaea, and micro-eukaryoes, along with their … By understanding how microbes contribute to ecosystem functions, the Program helps drive innovations that could … communities to uncover the complex interactions and functions that shape ecosystems. By decoding the microbial …

… The CSP Functional Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them translate genomic …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … better understanding of microbial communities and ecosystem function.  The Environmental Genomics group also hosts the Viral Genomics group . … of microbial ecology and metabolism by elucidating the functional potential of hard-to-culture microorganisms. This …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing … with some of the latest developments in microbial genomics, metagenomics, and computational biology, and to …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … are influenced by microbial partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and spatial transcriptomics barcode-based …

… a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential … types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes from … of host-virus interactions, the exploration of the functional dark matter as well as the development of novel …