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… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and … to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic …

… Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial …

… and environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a powerhouse. Rumen … materials, rumen microbes and their enzymes are an optimal study subject that could lead to more sustainable energy …

… about natural products and the science and scientists of secondary metabolism. Welcome back. This will be episode 12 of … ALISON TAKEMURA: So Nadine, what got you interested in studying natural products? NADINE ZIEMERT: Like almost … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …

… about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of … like, and then you could characterize it. The classical study that demonstrated this is Challis et al, Chemistry and … and archaeal genomes that were created – these are Metagenome Associated Genomes, or MAGs. So these are genomes …

… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hi, again. This is Dan, and you’re … secrete a lot more things than people do…? Although I don’t study people so maybe I’m wrong. But yeah, I mean, because I … them as very small fungi. And this came from a growth on a cow’s cheek. Historically, before antibiotics were common, …

… to identify over 27,000 microbial genes. The data from that study is now used across California State University campuses for biotechnology education as part of a course-based undergraduate resource … the chair of the JGI User Executive Committee, on how that study went from the lab to the classroom. …

… which includes the Sequencing Technologies team, relies on collaborations with Science Programs and Operations teams to enable the JGI’s focus on expanding molecular … An assay used for profiling transcription factor binding sites across entire genomes. This … high-throughput processing of samples in 96-well plates on automated liquid handler platforms, substantially …

… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . … And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But …

… The Micro-Scale Applications group explores the genetic makeup of natural microbial … the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … internal analytical standards to accurately measure environmental microbiome activity levels.This functional assay …