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    Maize can produce a cocktail of antibiotics with a handful of enzymes. (Sam Fentress, CC BY-SA 2.0)
    How Maize Makes An Antibiotic Cocktail
    Zealexins are produced in every corn variety and protect maize by fending off fungal and microbial infections using surprisingly few enzymes.

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    The genome of the common fiber vase or Thelephora terrestris was among those used in the study. (Francis Martin)
    From Competition to Cooperation
    By comparing 135 fungal sequenced genomes, researchers were able to carry out a broader analysis than had ever been done before to look at how saprotrophs have transitioned to the symbiotic lifestyle.

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    Miscanthus grasses. (Roy Kaltschmidt/Berkeley Lab)
    A Grass Model to Help Improve Giant Miscanthus
    The reference genome for M. sinensis, and the associated genomic tools, allows Miscanthus to both inform and benefit from breeding programs of related candidate bioenergy feedstock crops such as sugarcane and sorghum.

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    Poplar (Populus trichocarpa and P. deltoides) grow in the Advanced Plant Phenotyping Laboratory (APPL) at Oak Ridge National Laboratory in Tennessee. Poplar is an important biofuel feedstock, and Populus trichocarpa is the first tree species to have its genome sequenced — a feat accomplished by JGI. (Image courtesy of Oak Ridge National Laboratory, U.S. Dept. of Energy)
    Podcast: Xiaohan Yang on A Plantiful Future
    Building off plant genomics collaborations between the JGI and Oak Ridge National Laboratory, Xiaohan Yang envisions customizing plants for the benefit of human society.

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    Expansin complex with cell wall in background. (Courtesy of Daniel Cosgrove)
    Synthesizing Microbial Expansins with Unusual Activities
    Expansin proteins from diverse microbes have potential uses in deconstructing lignocellulosic biomass for conversion to renewable biofuels, nanocellulosic fibers, and commodity biochemicals.

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    High oleic pennycress. (Courtesy of Ratan Chopra)
    Pennycress – A Solution for Global Food Security, Renewable Energy and Ecosystem Benefits
    Pennycress (Thlaspi arvense) is under development as a winter annual oilseed bioenergy crop. It could produce up to 3 billion gallons of seed oil annually while reducing soil erosion and fertilizer runoff.

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    Artistic interpretation of CheckV assessing virus genome sequences from environmental samples. (Rendered by Zosia Rostomian​, Berkeley Lab)
    An Automated Tool for Assessing Virus Data Quality
    CheckV can be broadly utilized by the research community to gauge virus data quality and will help researchers to follow best practices and guidelines for providing the minimum amount of information for an uncultivated virus genome.

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    Unicellular algae in the Chlorella genus, magnified 1300x. (Andrei Savitsky)
    A One-Stop Shop for Analyzing Algal Genomes
    The PhycoCosm data portal is an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, compare them, and visualize supporting experimental data.

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    Artistic interpretation of how microbial genome sequences from the GEM catalog can help fill in gaps of knowledge about the microbes that play key roles in the Earth's microbiomes. (Rendered by Zosia Rostomian​, Berkeley Lab)
    Podcast: A Primer on Genome Mining
    In Natural Prodcast: the basics of genome mining, and how JGI researchers conducted it in IMG/ABC on thousands of metagenome-derived genomes for a Nature Biotechnology paper.

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    Scanning electron micrographs of diverse diatoms. (Credits: Diana Sarno, Marina Montresor, Nicole Poulsen, Gerhard Dieckmann)
    Learn About the Approved 2021 Large-Scale CSP Proposals
    A total of 27 proposals have been approved through JGI's annual Community Science Program (CSP) call. For the first time, 63 percent of the accepted proposals come from researchers who have not previously been a principal investigator on an approved JGI proposal.

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    MiddleGaylor Michael Beman UC Merced
    How to Successfully Apply for a CSP Proposal
    Reach out to JGI staff for feedback before submitting a proposal. Be sure to describe in detail what you will do with the data.

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    Click on the image or go here to watch the video "Enriching target populations for genomic analyses using HCR-FISH" from the journal Microbiome describing the research.
    How to Target a Microbial Needle within a Community Haystack
    Enabled by the JGI’s Emerging Technologies Opportunity Program, researchers have developed, tested and deployed a pipeline to first target cells from communities of uncultivated microbes, and then efficiently retrieve and characterize their genomes.

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    Artistic interpretation of how microbial genome sequences from the GEM catalog can help fill in gaps of knowledge about the microbes that play key roles in the Earth's microbiomes. (Rendered by Zosia Rostomian​, Berkeley Lab)
    Uncovering Novel Genomes from Earth’s Microbiomes
    A public repository of 52,515 microbial draft genomes generated from environmental samples around the world, expanding the known diversity of bacteria and archaea by 44%, is now available .

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    Green millet (Setaria viridis) plant collected in the wild. (Courtesy of the Kellogg lab)
    Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
    In Nature Biotechnology, a very high quality reference Setaria viridis genome was sequenced, and for the first time in wild populations, a gene related to seed dispersal was identified.

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    The Brachypodium distachyon-B. stacei-B. hybridum polyploid model complex. (Illustrations credits: Juan Luis Castillo)
    The More the Merrier: Making the Case for Plant Pan-genomes
    Crop breeders have harnessed polyploidy to increase fruit and flower size, and confer stress tolerance traits. Using a Brachypodium model system, researchers have sought to learn the origins, evolution and development of plant polyploids. The work recently appeared in Nature Communications.

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All JGI Features
Home › Podcasts › Natural Prodcast
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December 22, 2020

Natural Prodcast Episode 12: Nadine Ziemert

Natural Prodcast podcast logoContinuing the Natural Prodcast series on genome mining, guest Nadine Ziemert from the University of Tübingen on the evolution of secondary metabolite pathways as viewed through metagenome studies, and what more JGI and others can do to enable progress in this area of natural products. [Read More]

November 24, 2020

Natural Prodcast Episode 11: Marnix Medema

In this Natural Prodcast podcast episode, Marnix Medema of Wageningen University and his collaborators have a fantastic set of software tools for exploring secondary metabolite biosynthetic gene clusters (BGCs). [Read More]

November 9, 2020

Natural Prodcast Episode 10: A Primer on Genome Mining

Natural Prodcast podcast logoIn this Natural Prodcast episode, the basics of genome mining, including an analogy involving the California Gold Rush. Also covered: a new publication out of JGI in Nature Biotechnology. [Read More]

May 28, 2020

Natural Prodcast Episode 9: Roger Linington

In this episode of the Natural Prodcast, guest Roger Linington from Simon Fraser University talks about the Natural Product Atlas, a high-quality freely-available natural products structure database developed produced by a large international collaboration. [Read More]

May 7, 2020

Natural Prodcast Episode 8: Eric Schmidt

This episode of the Natural Prodcast podcast features guest Eric W. Schmidt from the University of Utah, a natural products chemist who works in a wide variety of marine organisms. The interview was conducted at the SIMB Natural Products conference in January 2020. [Read More]

April 21, 2020

Natural Prodcast Episode 7: Ben Shen

Natural Prodcast podcast logoEnediynes, enabling technologies, and leveraging a large microbial strain collection for natural product discovery. In Episode 7 of Natural Prodcast, Ben Shen from The Scripps Research Institute (TSRI) chats with Dan Udwary and Alison Takemura about enediynes and their use in medicine, how Ben got fascinated with natural products by working on terpene chemistry, TSRI’s acquisition of the Pfizer strain collection, and our collaborations to sequence that collection, mine genomes, and develop new technology to access natural products. [Read More]

April 6, 2020

Natural Prodcast Episode 6: Marc Chevrette

This episode of the Natural Prodcast podcast, features a conversation with Marc Chevrette. Marc is a postdoctoral fellow in Jo Handelsman’s group at the University of Wisconsin-Madison, where, among lots of other things, he works on the Tiny Earth project. [Read More]

March 27, 2020

Natural Prodcast Episode 5: Brad Moore

In this episode of the Natural Prodcast podcast, a conversation with Brad Moore, who has joint appointments at UC San Diego and Scripps Institution of Oceanography. The podcast interview was conducted during the SIMB Natural Products conference. [Read More]

March 25, 2020

Natural Prodcast Episode 4: Nancy Keller

In this Natural Prodcast episode, Dan Udwary and Alison Takemura chat with Nancy Keller, a fantastic fungal natural products researcher from the University of Wisconsin-Madison. The podcast was recorded at the Society for Industrial Microbiology’s Natural Products conference. [Read More]

March 18, 2020

Natural Prodcast Episode 1: The Primer, Part 1

This is Part 1 of Natural Prodcast’s primer on secondary metabolism. Natural Prodcast is available on Apple, Google, Spotify, Stitcher, directly with the RSS link, and via most other commonly-used podcast feeds. Please subscribe, and leave a review! [Read More]
Page 1 of 212»

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