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DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … It kind of looks like a sock puppet of a Yeti with a large purple lollipop attached to its mouth. We’ll have to put a …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …

… of viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions. ISME J. … et al. (2019) Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth’s biomes. Nature …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … they spread, why do they spread in a certain way from one bacteria to another, how do they change then, and why are … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… manipulation in the laboratory. Both germplasm (sequenced mutants and natural accessions) and protocols …

… cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … This is a dynamic and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, whereby they can modulate host …

… work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more progress faster, … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, … of horizontal gene transfer. … The SMC provides complete sequence and annotation data for secondary metabolite …