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… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … drive innovations that could advance our understanding of Earth’s ecosystems. … such as quantitative stable isotope probing (qSIP)-metagenomics and metatranscriptomics, to metagenomics and …

… well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our … through end-to-end automation — and further advancing sequence applications, single cell genomics, DNA synthesis, … [QA/QC]), large-scale liquid handling automation, and sequence analysis. …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and … Exploring the fascinating world of giant viruses, which challenge our understanding of viral …

… develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct … and viral diversity, leading to a better understanding of microbial communities and ecosystem function.  The … Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of …

… When submitting sequences to the JGI DNA Synthesis program, please include … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an … add the characters “.gb” (no quotes, just .gb) to the end of your file name. …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … a mixture of, for example, metatranscriptome sequencing, metagenomics, single cell genomics. We even do the flow … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… Below is a brief description of the process needed to prepare and ship samples for … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting … step for many projects at the JGI. The quality of the starting material is one of the greatest predictors …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal … microorganisms, by sequencing large populations of bacteria and archaea in their natural environments using …