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The JGI’s Microbial Program focuses on using cutting-edge sequencing, … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from … tools for analyzing the functional capability of microbial communities based on their metagenome sequence, in the …

But most people that know me call me Kate. Dan Udwary: Great. So we’ve got Kate here today, and we wanted to talk … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses … activity across ecosystems.  By studying microbial communities and their interactions, the Program aims to … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … But we’re not just here to talk about us. We have a great person to talk to tonight. We have Nadine Ziemert from … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… the world. … But, meanwhile, I’ve been sitting on all these great interviews recorded a few months ago at the SIMB … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… genomic data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The Integrated Microbial Genomes group is focused on:  Developing … distribution of microbial genome and microbiome datasets sequenced at the JGI. IMG/M is also open to scientists …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … that just melts in your hands, that’s not going to be great to work with. If you have an icy, hard packed snowball … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… be hearing about microbiology and natural products from the Great Salt Lake, and you’re going to learn, like me, what a … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … and where we are today. After that, we have lots of great conversations that we’ve already recorded with some … tell.  ALISON: It could be bacterial blankets, or coats, or water bottles, in a metaphor…. DAN: Or because they’re …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … scientists who also do genome mining. We’ve got a great, fun bunch of little shows lined up, and I’m really … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… is the podcast for you. A lot of this is based on a really great paper that came out in 2020 where this is all … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …