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Metagenome Program
The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and … into microbial ecosystems.  The Program also aims to build a global-scale catalog of viral, microbial, and …
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Single Cell Research Group
Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic … ., Ivanova N. N., Kelly W. J. Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection.” … discovery of biomass-degrading genes and genomes from cow rumen. Science 331, 463-7 (2011). Newton I.L., Woyke T …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
In honor of the JGI's 25th anniversary in 2022, we have … and environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a … fuels from plants is the high cost and resource requirements of processing these sturdy materials, rumen …
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Natural Prodcast Episode 12: Nadine Ziemert
… about natural products and the science and scientists of secondary metabolism. Welcome back. This will be episode 12 of … or the genes that you are analyzing. And then we’re building phylogenies a lot, making phylogenetic trees, and … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …
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How to Submit Sequencing Samples
Below is a brief description of the process needed to prepare and ship samples for … . … 1) Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable … sends Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of … the pieces that attached to the other pieces, and sort of building out the puzzle from there to find that vein of gold. … if an order is uncultured (blue; represented only by metagenome-assembled genomes or MAGs) or cultured (gray; …
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IMG Group
The IMG group owns and maintains integral components of JGI’s production workflow, and is responsible for … specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within … the IMG/M data release policy and follow the metadata requirements for integrating data into IMG/M (see IMG/M …
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JGIota: Looking Back at How Cow Rumen Samples Landed on a Syllabus
Back in 2011, JGI-supported researchers published a paper in the … to identify over 27,000 microbial genes. The data from that study is now used across California State University campuses for biotechnology education as part of a course-based undergraduate resource …
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How To Use Our Systems
… … Information on Software Looking for information on our software, including BBTools ? …
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Micro-Scale Applications Group
The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that utilize microfluidics/microdroplet technology in order to enhance the …
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Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen
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Microbial Program
The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated … capability of microbial communities based on their metagenome sequence, in the context of reference isolate …
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