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… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … research.  These efforts include exploration of the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of …

… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … along with their associated viruses and mobile genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses several …

The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the … of high performance plants and microbes, and understanding microbiome interactions. The  insights derived are crucial …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … ALISON TAKEMURA: I know that it’s looking in the genome for genetic elements of interest, you know, something like … Yeah, bacteria sound like a good place, to me, to look for diversity because there are so many bacteria, because it is …

Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … still persists to date. Research Team    … Phylogenetic diversity estimates show that the gap between cultivated and …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … my Peace Corps volunteer stint, and that it was in all the maize. So the main food that you ate was called Papa, which … looking at that I’m a very visual person. So, when we make genetic mutants in a fungal isolate, I can see something …

JGI Mission As a U.S. Department of Energy Office of Science user facility supported by the … … Microbes constitute the largest reservoir of biodiversity and functional versatility on Earth. Their … are at the core of many environmental processes, and the genetic makeup of microbial species and communities forms …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … coding potential to find novel functions that may impact microbiome structure and biogeochemical cycles. Research … Schulz, C Abergel, T Woyke (2022) Giant virus biology and diversity in the era of genome-resolved metagenomics. Nature …

… develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … Our aim is to more fully capture microbial and viral diversity, leading to a better understanding of microbial … Ladau, J. et al. (2019)  Spatial, Temporal, and Phylogenetic Scales of Microbial Ecology . Trends Microbiol. …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of … the program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … & Offerings … BOOST … Integrated Microbial Genomes and Microbiomes … Mycocosm … Phytozome … Inventory of Composable …

See below for examples of successful Letters of Intent to our Community Science … PIs who drafted them.  … Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated … in a cosmopolitan and abundant soil bacterium: genetic microdiversity or core metabolic flexibility? … Microbial …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … program aims to tap into the largely unexplored biochemical diversity within secondary metabolites, expanding their … uncover these hidden biochemical resources by exploring the genetic pathways responsible for their synthesis. The …