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Metagenome Program
The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and … to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the …
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Natural Prodcast Episode 14: Nigel Mouncey
… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . … And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But …
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Natural Prodcast Episode 19: Bill Fenical
… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the … kept looking for open jobs that said, we want a chemist to study the ocean. And I didn’t find a single job … in chemistry with a hobby of putting your head underwater. But thankfully that worked out. And I spent 30, 40 …
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Natural Prodcast Episode 20: Brian Bachmann
… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. … Do you go after sediment? Do you go after– if there’s any water– or I guess, when you’re down there, is it something … just now switching from intermicrobial interactions, studying intermicrobial interactions by imaging interactions …
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Natural Prodcast Episode 12: Nadine Ziemert
… about natural products and the science and scientists of secondary metabolism. Welcome back. This will be episode 12 of … ALISON TAKEMURA: So Nadine, what got you interested in studying natural products? NADINE ZIEMERT: Like almost … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …
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Microbial Program
The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated … capability of microbial communities based on their metagenome sequence, in the context of reference isolate …
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Natural Prodcast Episode 17: Cassandra Quave
… curator there, with a broad range of experimental work on plants for drug discovery in antibiotics, anticancer, and … And for the audience, ethnobotany is the scientific study of the ways that people interact with plants, whether … every year in the US and it has since 2005 even though we technically have a number of different antibiotics in our …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of … like, and then you could characterize it. The classical study that demonstrated this is Challis et al, Chemistry and … if an order is uncultured (blue; represented only by metagenome-assembled genomes or MAGs) or cultured (gray; …
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IMG Group
The IMG group owns and maintains integral components of JGI’s production workflow, and is responsible for … specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within … resource for analysis and annotation of genome and metagenome datasets in a comprehensive comparative context. …
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Micro-Scale Applications Group
The Micro-Scale Applications group explores the genetic makeup of natural microbial … out new approaches that utilize microfluidics/microdroplet technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … …
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Natural Prodcast Episode 16: Marcy Balunas
… … DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. … now?  MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … Marcy. So I was wondering, how did you get interested in studying natural products?  MARCY: That is a great question …
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How to Submit Sequencing Samples
Below is a brief description of the process needed to prepare and ship samples for … sends Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your … to fill out (or provides a link to complete the form online) PI completes and returns the spreadsheet to the PM …
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