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… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One … of which belong to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. …

… automation — and further advancing sequence applications, single cell genomics, biodesign, and metabolomics capabilities.    … JGI operates highly scaled short- and long-read sequencing pipelines. This includes advanced sample management (quality … method allowing high-throughput processing of samples in 96-well plates on automated liquid handler …

… brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on accessing sample-level reports and tracking statuses.  Please … detailing the quantity & quality requirements for samples submitted to the DOE JGI. DNA Preparation Guidelines …

… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts … Genomics group attempts to address this question in natural soil ecosystems by combining metagenomics with other omics …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal analytical standards to …

… addressing key environmental challenges, such as improving soil health, carbon sequestration and bioeconomy … of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic … and improved draft microbial genomes the program offers single-cell sequencing, resequencing, RNA sequencing and …

… We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … possess genomes and particle sizes that rival those of cellular organisms. Giant viruses challenge the traditional boundaries between viruses and cellular life, providing unique insights into viral …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway … product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw data … repository . Not all products are available for all proposal calls.   Please review the call language carefully to …

… the program supports foundational research related to soil nutrient cycling and health, terrestrial biogeochemical … from a wide range of biological and environmental samples — including microbes, fungi, plants and soils. Through a combination of experimental workflows and …

… is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … DAN: Yeah, I don’t think your lab is gonna tackle that single handedly, right? So, yeah, getting the community … our lead into the product. So we are able to enrich the pipeline, for big pharmas like Pfizer will be able to really …

… convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for … — including strain engineering — to make them more user accessible Synthetic Biology Informatics Group : a team that … to validate hypotheses generated from mining genomic data by designing and assembling physical DNA constructs that can …

… multiple DOE National User Facilities in one research proposal.  Successful applications will focus on high-risk/high-payoff … beyond what each of these facilities could generate by itself.   Accepted projects must address or be otherwise … User Facilities, as well as DOE. Nearly all LOIs are accepted for full proposal submission, with the primary …