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… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … flavors. So non-heme enzymes, it just means that they need iron. DAN UDWARY: Right. ALISON NARAYAN: They have iron in …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … These insights are crucial for addressing key environmental challenges, such as improving soil health, carbon … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … so far no species or no strains known that really grow in freshwater. But they’re actually pretty orange, and they … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … will actually chelate any divalent metal. So it could be iron, could be silver, it could be copper, but unless you … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … your opinion then on bioprospecting in sparse nutrient environments versus the tropics? Because like you say there is … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … a program that involves researching the local marine environment. I went out and picked up marine plants, I picked … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … Institute is under the DOE’s mission of energy and environment. And so we know that lots of different types of … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … a bunch of microbes, all talking to each other in every environment you can think about.   DAN: What kind of genomic …

… cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … and spatial transcriptomics to profile the plant/environmental interface. We are using these methods to … Interactions … Single-cell characterization of plant/environmental responses … Selected Publications … Research Team …

So lots of reasons that I was attracted to work in that environment. Yeah, so that was here in San Diego. So yeah, so I … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …