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… foreshadow climate change impact on marine microbial communities. The Science A team of researchers tracked the impact … of a large-scale heatwave event in the ocean known as “The Blob.” The event was recorded during a long-term study of … as hurricanes and droughts. Another one began in late 2013, when a large patch of warm ocean water about a third the …

… way to find things is by comparison. We’ll talk about that when we talk about molecular biology.  But um, yeah, so … metabolism, they are copies and changes that nature has made. So secondary metabolism is adaptation of primary … photograph, or one corner of it, you see this big white blob – sort of overexposed – but this this white blob is a …

… listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and … potential application perspective, is because this compound when they were first structurally resolved in the 1980s, … of biology.  DAN: That’s right.  BEN: You know, to say, man-made compounds. How can you design a drug, right? You design …

… maybe being similar to – I used to use a computer analogy when I was teaching it to people who are outside the field. … that clean. And so each of those little domains is a little blob of protein that’s, you know, wiggling around in the … say you knew you had a molecule. And you knew that if you made this change, which might be a small change, might be a …

… earlier this year. And today we have our conversation with Professor Alison Narayan, from the University of … trained in synthetic chemistry as were you and then made their way into the field of natural products in some … a lot about this as well like is specificity good or bad when it comes to biocatalysis? You want your reactions to be …

… by the sea in the northeast of Scotland. It was actually when I was traveling at the end of first year University. … which caused no end of confusion. And we actually made up a quarter of the master’s class, because there were … age, for sure. Dan Udwary: –with the yellow and orange blobs on it. Kate Duncan: Yeah, so I feel like this is a bit …

Every approved proposal starts with a User Agreement — before any work can begin, including … the type of work or specific proposal to be covered under the Agreement. The signing official must have the … approved by the DOE to address the DNA Synthesis program. When fully executed, the new User Agreement will replace the …

… to the “Self Promotion Episode” of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but … and the transcripts will be one thing I can point people to when it comes to getting out information about both SMC, and … of the molecules and then looking at how they were made was really interesting and intriguing to me. And I …

… listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a podcast about natural products … it’s sort of an introduction to secondary metabolism. And when we were talking about definitions around words I made a possibly false statement. I said that I thought that …

First and foremost, our interview this week is with Professor Brian Bachmann from Vanderbilt University’s … Ecopia, which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … So Brian and I– Brian was the very first recording I ever made practicing for the podcast. And– I did not know what I …

… got a great episode for you here today. We got the opportunity to talk to one of the real legends of natural products, … a big diver at the time? BILL FENICAL: I had begun diving when I was a teenager, about 15. I grew up in Northern … try to prove it, was just not known. And the first time I made that comment here at Scripps to our very, very …

… listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and … of how many times Brad used the words “fun” and “magical” when describing his science, which is kind of the hallmark … Dan: Yeah. So when I talk to Brad, this is when I get made fun of. So yeah, this will be fun. All right. Brad: …