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DOE Metrics
… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) …     2,208     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total … 2,208 102.0% *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total …
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Viruses Reprogram Cells into Different Virocells
… Microbial cells infected by viruses undergo metabolic reprogramming. … A portion of this research was performed under the Facilities Integrating Collaborations for … an award to MBD and MBS (#2582) and used resources at the DOE Joint Genome Institute and the Environmental Molecular …
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Single Cell Research Group
… material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the … of  function-driven single-cell genomics . Here, single cells are characterized and selected as based on a specific …
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New Lineages of Life Group
… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … Exploring the fascinating world of giant viruses, which challenge our understanding of viral … viruses and cellular life, providing unique insights into viral evolution and complexity, and encode for a …
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Viral Genomics Group
… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of … from metagenomes, our understanding of the impacts of these viruses on microbiome processes is still limited. One key …
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Natural Prodcast Episode 7: Ben Shen
… for every episode we put out. I actually put a lot of time into preparing those transcripts, so I hope somebody’s going … of electrons that becomes really reactive. And so, different types of enediyne molecules can bind to different … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: …
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Institutional User Agreements
… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is a …
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Publication Policy
… research project are appropriately recognized and credited for their work, while also adhering to the authorship … and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts to do so, and JGI expects …
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Micro-Scale Applications Group
… of single-cell genomes and directly link functional information with individual cells. Research Team    … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity … (BONCAT+FACS). To provide additional functional insights into microbial genomes, the JGI now uses laser …
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Natural Prodcast Episode 18: A CSP Primer
… idea that fits within our mission, we’re happy to help you figure out if it’s a good fit. Everyone we talked to said … bit confusion about what a CSP is as opposed to other different kinds of federal grants like through NIH or NSF … genomes. Fungal plant, algal genomes, a lot of effort goes into generating these data sets. There’s a lot of manual …
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Natural Prodcast Episode 1: The Primer, Part 1
… Secondary Metabolites Science Program, which I was hired into, and my job is to do cool research, and also to talk to … they figured out that they could culture the plant cells and produce enough that way in really large like 7500 … experience some natural products now but maybe that’ll be a different episode. I mean, I’m sure we are experiencing some …
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Plant Microbial Interactions Group
… symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of … experimental characterization methods, in addition to bioinformatics tools to elucidate phage function in this …
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