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The JGI’s Microbial Program focuses on using cutting-edge sequencing, … genome sequencing of underexplored bacterial and archaeal lineages that are important for bioeconomy applications. By … of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve …

… and machine learning to identify new divergent lineages and expand the Tree of Life. We then investigate … of a giant virus. mSystems. 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature …

Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other projects in … A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et … Acids Res.  45(D1):D457-D465. Paez-Espino, D. et al. (2016) Uncovering Earth’s virome.  Nature   536:425-30 Kyrpides NC. …

… interactions with their environments and with each other, from defending against predators to aiding in symbiotic … (BGCs) being expressed. The program works to uncover these hidden biochemical resources by exploring the genetic … broader goal of enhancing biotechnological applications, from biofuel production to improving the resilience and …

… program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will … of Energy Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though … … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed with some of …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties encoded …

… genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses … regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential to drive innovations in … searches to expand representation of uncultivated microbial lineages. Charting viral ‘dark matter’:   Viruses are …

… our interview this week is with Professor Brian Bachmann from Vanderbilt University’s Chemistry Department, where he … and then in terms of there’s sequencing an organism by shotgun, which is what we did, we didn’t even sequence the … of thought with that. So some people are interested in cave microbial– people are interested in the more extreme …

… exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — … systems can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   …

… genomic data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The Integrated Microbial Genomes group is focused on:  Developing … species specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control …

… in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated … as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic potential of uncultivated lineages is of high value to establish models and …

… studied chemistry, because she switched her degree program from geography to chemistry. So we were both enrolled as … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is … and culture things under lab settings, we’re getting a snapshot in an artificial environment. And if we really want to …