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… that grow on one-carbon compounds like methanol and methane. And I really dove into microbial physiology and … of these bacteria that eat methane, so they can use methane gas as their sole source of carbon and energy. And it was … ecology community to be able to better predict how their microbes are interacting with each other from sequence …

… secrete a lot more things than people do…? Although I don’t study people so maybe I’m wrong. But yeah, I mean, because I … of bacteria and the things that they’re doing in the human gut. Turns out, there’s a lot of chemistry happening there – … common, it wasn’t unusual to see sort of weird growths on livestock due to you know, bacterial or fungal infections. …

… and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other projects in the group include … Neri U. et al. (2022) Expansion of the global RNA virome reveals diverse clades of bacteriophages. Cell . … compendium of 189,680 DNA viruses from the human gut microbiome. Nat Microbiol . 6(7):960-970. Nayfach S, et …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … kept looking for open jobs that said, we want a chemist to study the ocean. And I didn’t find a single job … you think about the fact that, when plants and animals and microbes evolve, they evolve to make molecules that improve …

… product reports on the evolution of genome mining and microbes with Mohammad Alanjary and Tilmann Weber to be a … ALISON TAKEMURA: So Nadine, what got you interested in studying natural products? NADINE ZIEMERT: Like almost … talked about at the JGI meeting. DAN UDWARY: What’s your gut feeling about that sampling? Do you find different …

… what was this bacterium, and why did your group want to study it? Marnix Medema: You mean the PhD project that I … We got so many submissions. But indeed, people are still contributing this data and that’s fantastic too. That indeed … a nice example of going from a whole community with many microbes, hundreds of gene clusters, and then being able to …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … was adjacent to what I worked on, but my experience of how microbes are interacting in the environment like, like my … I’m definitely seeing why this is such an important area to study. Okay, what’s your third story?  DAN: The third story …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … At the end of the day, all the content produced by microbes the result of millions of years of evolution. And … genome mining software we mentioned: “ EvoMining reveals the origin and fate of natural product biosynthetic …

… now?  MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … bacteria so what’s – I guess that maybe you could say the gut is, kind of. But not the same way this is designed … activity. So the chemistry and function really of those microbes that live there.  And in our work we’ve determined …

Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today we’re going to talk to Kate Duncan. And Kate is– I should ask, you … I wouldn’t say I was one of these people that wants to study oceanography and was fascinated by the oceans, though … what’s important in terms of the chemistry produced by microbes. And by what’s important, I mean, like, where …

… is Professor Cassandra Quave from Emory University, with joint appointments in the School of Medicine and College of … And for the audience, ethnobotany is the scientific study of the ways that people interact with plants, whether … and take soil and discover a new important drug from the microbes in that soil, there are now international …

We count on livestock for food and fiber, but raising these animals also … gas: methane. Those emissions mainly come from gut microbes — the bacteria and archaea breaking down plant … matter. So since 2010, the JGI has supported researchers studying those microbial methane-makers. Eventually, that …