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DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … find, things that are of interest. And usually, in terms of bacteria and secondary metabolism, those things that we want …

… welcome, Nadine. ALISON TAKEMURA: What is the big picture for you in your lab? NADINE ZIEMERT: Big picture, I want to … they spread, why do they spread in a certain way from one bacteria to another, how do they change then, and why are … the other genome, and we hybridized it at the time with the radioactively labeled probes. And I never thought it would …

… about something I can kind of see like the squid and the bacteria and how the chemistry is going back and forth between them is part of what fascinates me about what … but of course is not. And so we’ve been working with metals and in particular rare earth elements or Rare Earth …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can …

… and resources. Our vision is to lead genomic innovation for a sustainable bioeconomy. ALL PROPOSALS must support the … energy and environmental mission objectives. Fungi, algae, bacteria, archaea, viruses, and microbial communities of … or are energetically coupled to contaminants such as heavy metals or radionuclides in soils, freshwater, coastal …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the 40,000 from bacteria, there’s …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … on synthetic biology of engineering gene expression in bacteria – however, the professor was actually quite …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … in the marine ecosystems and marine actinomycetes and cyanobacteria. And we thought we could also– let’s see what caves …

Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … on identifying and characterizing haloperoxidases from bacteria. And with Christian, I started getting a little bit … which can range from 8% to 28% salinity. We have toxic metals, so these concentrations of arsenic and lead and …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … inter-organismal interactions. These insights are crucial for addressing key environmental challenges, such as …

… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the opportunity to talk to one of … of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working …

… fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … experimental characterization methods, in addition to bioinformatics tools to elucidate phage function in this …