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Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer of marine … into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working … we were studying marine animals, marine plants, things like sponges and things you could collect. But when we’d find …

And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more progress faster, … interesting. He was interested to know how animals in the ocean use chemistry to interact and it went from there.  … What animals? ERIC:  So he was really a specialist on sponges. And he’s worked on lots of different creatures. And …

… focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which … reservoir of secondary metabolites produced by bacteria, fungi, algae and plants. These compounds are key … (BGCs) being expressed. The program works to uncover these hidden biochemical resources by exploring the genetic …

Brad Moore, UC San Diego and Scripps Institution of Oceanography. (Courtesy of B. Moore) DAN: This is the second … it be a plant or from the bottom of the ocean, from a sponge, or a seaweed, were just having just remarkable … Initially, my group really focused on marine actinobacteria. Then we moved into marine proteobacteria. Not a …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in … of a giant virus. mSystems. 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature … 1-9 Schulz et al. (2017) Towards a balanced view of the bacterial tree of life. Microbiome. 5 (1), 1-6 Schulz et al. …

… about something I can kind of see like the squid and the bacteria and how the chemistry is going back and forth … you would think. Anything that could be swimming in the ocean right?  ALISON: Follow up question: Does the organ … can be controversial. People use cryptic, or silent, or hidden, obscured. But mostly it means that we– especially …

… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … to explore microbial diversity — with an emphasis on bacteria and archaea, and including those associated with … microorganisms, by sequencing large populations of bacteria and archaea in their natural environments using …

… cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … This is a dynamic and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, whereby they can modulate host …

… wouldn’t say I was one of these people that wants to study oceanography and was fascinated by the oceans, though I’ve always lived by the sea in the northeast … biology classes in undergrad, but my PhD was an actinobacteria. And I tell all my students this now, but when I …

… through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … that are known to be sources of secondary metabolites, like sponges were a really common source for people to try to … come from bacteria that actually live within, say, the sponges or other things. And we know lots more about …

… in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … pulled from the soil, maybe it’s, you know, we talked about sponges, go pull a sponge or extract some tree bark. And so you’re just taking …

… chemical compounds that you find in plants, fungi and bacteria, basically all living things. When your crazy Aunt … studied microbial ecology. I studied Vibrio species in the ocean, so heterotrophic bacteria. Now, we didn’t get into … talk to you in a couple of weeks at Scripps Institution of Oceanography. He got me into genomics of microbes, …