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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… and Gene Integration . ACS Chem Biol. 2019 Apr 19;14(4):704-714. doi: 10.1021/acschembio.8b01107. Epub 2019 Apr … themselves for example using GNPS. Q:  Since the enzymes are doing the heavy lifting to make the metabolites, … see this  Metabolomics Data Analysis – Tips from Users page.  Q:  Is the metabolic study able to build a profile …
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iPHoP: A Matchmaker for Phages and their Hosts
… these hosts are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these … such as terrestrial soil, having additional isolates and metagenomic datasets will strengthen future virus-host … of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE Office of Science User Facility, is …
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Natural Prodcast Episode 19: Bill Fenical
… we want to talk a little bit about. It’s sort of early stages. But I think that is emblematic of some of the … underwater. But thankfully that worked out. And I spent 30, 40 years diving all over the world and bringing samples into … 20S proteasome. The proteasome in the cell is a bundle of enzymes that is used to degrade proteins, peptides, that are …
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A Shrubbier Version of Rubber
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Natural Prodcast Episode 2: The Primer, Part 2
… maybe obvious or notable. We are still in – not an early stage. I think we can identify most secondary metabolism … yeah. I mean, you might be producing things at different stages of growth or different signals from the environment … molecules and their discoveries over a stretch from 1940 to 2000. As you can see, from the 1940s, into the 50s …
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2025 NeLLi Symposium
Natarajan Google Olga Zhaxybayeva Dartmouth University … Metagenomic and single-cell sequence data have provided a … Dartmouth University See full agenda at the bottom of this page. … Check back for information on venue and lodging.  … … to space restraints. Poster Sizes: The poster boards are 4’x8′. Please be mindful in bringing posters that are at …
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Plant Pan-Genomics Comes of Age
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Streamlining Regulon Identification in Bacteria
… gene. These bacterial RNA polymerases are made up of a core enzyme complex as well as a sigma factor. While all bacteria …
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Better Genome Editing for Bioenergy
… created a set of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact … each guide in a  Y. lipolytica strain lacking a necessary enzyme for DNA repair. Whereas an effective sgRNA would lead … Institute grant  CSP-503076 (IW, HA, and MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval …
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Clades of huge phages from across Earth’s ecosystems
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… to  Euryarchaeota .  Finding Methane-Making Microbes with Metagenomics  By leveraging metagenomics to sample the entirety of a microbial community … explained. “Not only do you not know in which direction the enzyme these genes encode are used — so producing methane or …
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Glacier ice archives nearly 15,000-year-old microbes and phages
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