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… to the second episode of the Natural Prodcast. This is part 2 of our “primer” episode, so if you ended up here somehow … but traditionally, somewhere in the neighborhood of 60 to 70% of all of the medicines that we use are natural … to find something new. That started decreasing around the 1970s, you can see on the chart, and then things get a little …

… has been a pioneering effort in functional genomics since 2012, with a focus on addressing critical energy and … and bioproduct applications. The program has completed over 70 projects, including gene synthesis, combinatorial pathway … genome portals, we study lignocellulose decomposition, CO2 fixation, redox reactions, and plant metabolite …

… Yeah, that’s right. We were postdocs together in the mid 2000s, I guess. You were working for Brad Moore. I was … for those 50 journals. For – [it] varied -something like 20 years, and then we – I – forced the lab group to take a … about the topic we cared about. And that gave us about 12,000 molecules. And that was enough for us to build a basic …

… of this is based on a really great paper that came out in 2020 where this is all explained in detail, so if you’d like a … of years in these particular niches, produce probably 20 or 30 more metabolites, which have this particular …

… We don’t want to get a proposal that’s just asking for 20 microbial genomes. That is not a good fit for our annual … call where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a … high throughput sequencing capabilities. Such as sending us 20 DNA samples is also not a good fit for JGI, even for the …