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… genomes for just a small fraction of Earth’s microbial diversity. Because most microbes cannot be cultivated under … To acknowledge the efforts of the investigators who had done the sampling, Eloe-Fadrosh reached out to more than 200 … compared over 500,000 existing genomes available at that time. “Looking across the tree of life, it’s striking how …

… step in the deadly dance between a virus and microbial cell is an embrace. For a virus with a “head-tail” … of viruses that had in their genomes a surprising tool: a “diversity generating retroelement,” or DGR. The DGR could … only for viruses and other microbes , but for scientists. One emerging industry application of DGRs is to use them to …

… what the next five years of innovation could look like. In one article, Micro-Scale Applications head Rex Malmstrom and … metagenomics. One approach uses fluorescence-activated cell sorting (FACS) to sort cells into several small pools … nature. In the last few years, mapping the planet’s viral diversity has advanced drastically, aided by genome assembly …

… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as … synthesis of sustainable chemical products,” said Jewett, one of the study’s senior authors. “But this has been done … jump in the rate of product formation.” This was the first time CRISPR-Cas9 had been used to modify a cell’s genome in …

… for cutting-edge genomic research — and is capable of discovering and modelling complex biological sequences such … generate and manipulate the human language—are well positioned to help enhance our understanding of life’s genomic … foundation models. However, the sheer vastness of microbial diversity is not covered by reference genomes.”  Most of the …