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An Addiction Crucial to a Fungus’ Reproduction
… and Burkholderia endobacteria, a collaborative effort led by researchers at Cornell University and scientists at the … with the fungi and bacteria, while the DOE JGI team sequenced and annotated a host genome (Rm ATCC 52813) as … fungus reliant on the continued presence of the bacteria. By studying the Rm-Burkholderia symbiosis model, the team …
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Introducing New Members of the JGI User Executive Committee
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JGI Announces 2026 New Investigator Portfolio
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JGI@25: From Life at the Extremes to Editing Genomes
… for her work on CRISPR-Cas9, technology described by the Nobel Foundation as having “a revolutionary impact on … have partnered with JGI’s Microbiome Data Science group led by Nikos Kyrpides , mining the Integrated Microbial Genomics … CA. Banfield’s observations of the CRISPRs in her microbial sequences piqued Doudna’s interest. As Doudna noted in her …
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Defining a Pan-Genome for Antarctic Archaea
… have learned to adapt from marine to hypersaline conditions by studying the microbial communities in Antarctic lakes, … biogeography in the haloarchaeal gene pool, a team led by University of New South Wales (UNSW)-Sydney professor … Impact By collecting and sequencing dominant haloarchaeal sequences from six hypersaline lakes, researchers focused on …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
… Participation (CAMP) program, a statewide initiative funded by the National Science Foundation (NSF) that supports …
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SPRUCE-ing Up Science
… As a part of his internship, he was regularly tasked by his mentor to present his project work and navigate a … 2022 Jun;234(6):2111-2125. doi: 10.1111/nph.18072.   Byline: Ashleigh Papp …
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Streamlining Regulon Identification in Bacteria
… Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of regulon identification by in vitro transcription-sequencing (RIViT-seq) to … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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Gene Expression: From On-Off Switch to Dial
… on, scientists can determine the level of gene expression by the gradations. The Impact Metabolic engineering could … characteristics in an organism. The experiment was led by Hal Alper, professor and associate chair at the … These results show that this singular library synthesized by JGI was versatile enough for use in multiple …
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Gut Fungi: Unexpected Source of Novel Chemicals
… to help bolster the bioeconomy. Summary A team led by Michelle O’Malley, a chemical engineer at the University … horse in Massachusetts, in their hunt for anaerobic fungi. By growing extracts without oxygen in ruminant fluid — which … finnis . In work reported in 2017, the fungal genomes were sequenced by the U.S. Department of Energy (DOE) Joint …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… to activate multiple chemical production pathways. By tracking gene activity and chemical output over time, the … had never been mapped in this detail before.     The Impact By revealing how a single stress signal rewires a … The team also identified previously unknown promoter sequences within these gene clusters, offering new …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… and environmental remediation—all priorities identified by the DOE Office of Biological and Environmental Research … might contribute to the emergence of new pathogens. “ By sharing our vision broadly across Berkeley Lab, with …
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